Suppr超能文献

基于社区的减少瑞典衣原体流行的衣原体星期一干预措施的成本效益分析。

A cost-effectiveness analysis of the Chlamydia Monday--a community-based intervention to decrease the prevalence of chlamydia in Sweden.

机构信息

Karolinska Institute, Stockholm, Sweden.

出版信息

Scand J Public Health. 2010 Mar;38(2):141-50. doi: 10.1177/1403494809357260. Epub 2010 Jan 11.

Abstract

AIMS

The study was undertaken to assess the cost-effectiveness of the Chlamydia Monday, 2007. This is a community-based intervention aimed at reducing the prevalence of chlamydia by information and increased availability of testing, treatment and contact tracing in Stockholm. The aim was to analyze the cost-effectiveness by estimating costs, savings and effects on health associated with the intervention, and to determine if cost-effectiveness varies between men and women.

METHODS

A societal perspective was adopted, meaning all significant costs and consequences were taken into consideration, regardless of who experienced them. A cost-effectiveness model was constructed including costs of the intervention, savings due to avoiding potential costs associated with medical sequels of chlamydia infection, and health gains measured as quality adjusted life years (QALY). Sensitivity analyses were done to explore model and result uncertainty.

RESULTS

Total costs were calculated to be 66,787.21; total savings to 30,370.14; and total health gains to 9.852324 QALYs (undiscounted figures). The discounted cost per QALY was 8,346.05 (10,810.77/QALY for women and 6,085.35/QALY for men). Sensitivity analyses included changes in effectiveness, variation of prevalence, reduced risk of sequel progression, inclusion of prevented future production loss and shortened duration for chronic conditions. The cost per QALY was consistently less than 50,000, which is often regarded as cost-effective in a Swedish context.

CONCLUSIONS

The Chlamydia Monday has been demonstrated by this study to be a cost-effective intervention and should be considered a wise use of society's resources.

摘要

目的

本研究旨在评估 2007 年“衣原体星期一”的成本效益。这是一项基于社区的干预措施,旨在通过提供信息以及增加检测、治疗和接触者追踪的可及性,降低斯德哥尔摩衣原体的流行率。目的是通过估计与干预相关的成本、节省和对健康的影响来分析成本效益,并确定成本效益是否因性别而异。

方法

采用了一种全社会的观点,即考虑所有重要的成本和后果,无论谁经历了这些成本和后果。构建了一个成本效益模型,包括干预措施的成本、避免与衣原体感染的医疗后果相关的潜在成本的节省,以及用质量调整生命年(QALY)衡量的健康收益。进行了敏感性分析以探索模型和结果的不确定性。

结果

总成本计算为 66787.21 瑞典克朗;总节省为 30370.14 瑞典克朗;总健康收益为 9.852324 个 QALY(未贴现数字)。未贴现的每 QALY 成本为 8346.05 瑞典克朗(女性为 10810.77/QALY,男性为 6085.35/QALY)。敏感性分析包括有效性变化、流行率变化、继发进展风险降低、包括预防未来生产损失和缩短慢性疾病持续时间。每 QALY 的成本始终低于 50000 瑞典克朗,这在瑞典语境下通常被认为是具有成本效益的。

结论

本研究表明,“衣原体星期一”是一种具有成本效益的干预措施,应被视为明智地利用社会资源。

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验