Division of Epidemiology and Biostatistics, Rajendra Memorial Research Institute of Medical Science, Indian Council of Medical Research, Patna, Bihar, India.
Am J Trop Med Hyg. 2010 Jan;82(1):9-11. doi: 10.4269/ajtmh.2010.09-0235.
We estimated the level of under-reporting of visceral leishmaniasis (VL) cases by comparing the actual reported cases with those expected as estimated using age- and sex-stratified incidence proportions obtained in a cohort of 31,324 persons. The average incidence proportion of VL cases in study population was 5.7/1,000 (95% confidence interval [CI] = 4.88-6.54) and 1.09/1,000 persons (95% CI = 0.99-1.20) based on the reported cases in two primary health centers. The overall magnitude of VL cases not reported to the government agencies was higher by a factor 4.17 (95% CI = 3.75-4.63) than for reported cases. The levels of under-reporting were 4.74 (95% CI = 4.11-5.47) in males and 3.51 (95% CI = 2.99-4.11) in females with no significant difference (P > 0.05). It was significantly higher in persons >or= 30 years of age than in persons 30 years of age (P < 0.05).
我们通过将实际报告的病例与使用 31324 人队列中获得的按年龄和性别分层的发病率比例估计的预期病例进行比较，估计了内脏利什曼病（VL）病例的漏报水平。研究人群中 VL 病例的平均发病率比例为 5.7/1000（95%置信区间[CI] = 4.88-6.54）和 1.09/1000 人（95%CI = 0.99-1.20）基于两个初级保健中心报告的病例。与报告病例相比，未向政府机构报告的 VL 病例总体规模高出 4.17 倍（95%CI = 3.75-4.63）。漏报率为男性 4.74（95%CI = 4.11-5.47），女性 3.51（95%CI = 2.99-4.11），无显著差异（P > 0.05）。年龄≥30 岁的人群明显高于 30 岁的人群（P < 0.05）。
