三维重建细粒棘球蚴幼虫在人肝组织内的生长情况揭示了复杂的生长模式。
Three-dimensional reconstruction of Echinococcus multilocularis larval growth in human hepatic tissue reveals complex growth patterns.
机构信息
Institute of Hygiene and Microbiology, University of Würzburg, Würzburg, Germany.
出版信息
Am J Trop Med Hyg. 2010 Jan;82(1):126-7. doi: 10.4269/ajtmh.2010.09-0462.
Abstract
In this study we present, for the first time, a three-dimensional digital reconstruction of Echinococcus multilocularis larval growth in human tissue. Formalin-fixed, paraffin-embedded hepatic tissues from patients with alveolar echinococcosis were serially sectioned, stained, and areas of larval growth of the parasite were microphotographed. Parasitic structures were reconstructed from multiple digital planes, revealing a root-like network of interconnected vesicles and tubules extending into the periphery of lesions.
摘要
在这项研究中，我们首次展示了细粒棘球蚴幼虫在人体组织中生长的三维数字重建。对患有泡型包虫病的患者的福尔马林固定、石蜡包埋的肝组织进行连续切片、染色，并对寄生虫幼虫生长的区域进行显微摄影。从多个数字平面重建寄生虫结构，显示出一种类似根的相互连接的囊泡和小管网络，延伸到病变的外围。
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