Rac GTPases play multiple roles in erythropoiesis.
作者信息
Ji Peng, Lodish Harvey F
出版信息
Haematologica. 2010 Jan;95(1):2-4. doi: 10.3324/haematol.2009.015511.
Abstract
摘要
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Rac GTPases play multiple roles in erythropoiesis.Rac小GTP酶在红细胞生成中发挥多种作用。
Haematologica. 2010 Jan;95(1):2-4. doi: 10.3324/haematol.2009.015511.
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本文引用的文献
1
Rac1 and Rac2 GTPases are necessary for early erythropoietic expansion in the bone marrow but not in the spleen.Rac1 和 Rac2 GTPases 对于骨髓中的早期红细胞生成扩张是必要的，但在脾脏中则不是必需的。
Haematologica. 2010 Jan;95(1):27-35. doi: 10.3324/haematol.2009.006239.
2
Mammalian Rho GTPases: new insights into their functions from in vivo studies.哺乳动物Rho GTP酶：体内研究对其功能的新见解。
Nat Rev Mol Cell Biol. 2008 Sep;9(9):690-701. doi: 10.1038/nrm2476.
3
Enucleation of cultured mouse fetal erythroblasts requires Rac GTPases and mDia2.培养的小鼠胎儿红细胞的去核需要Rac GTP酶和mDia2。
Nat Cell Biol. 2008 Mar;10(3):314-21. doi: 10.1038/ncb1693. Epub 2008 Feb 10.
4
Rac GTPases regulate the morphology and deformability of the erythrocyte cytoskeleton.Rac小G蛋白调节红细胞细胞骨架的形态和可变形性。
Blood. 2006 Dec 1;108(12):3637-45. doi: 10.1182/blood-2006-03-005942. Epub 2006 Aug 1.
5
Generation of rac3 null mutant mice: role of Rac3 in Bcr/Abl-caused lymphoblastic leukemia.Rac3基因敲除突变小鼠的产生：Rac3在Bcr/Abl诱导的淋巴细胞白血病中的作用
Mol Cell Biol. 2005 Jul;25(13):5777-85. doi: 10.1128/MCB.25.13.5777-5785.2005.
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Generation and characterization of Rac3 knockout mice.Rac3基因敲除小鼠的产生与鉴定
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Rac2-deficient hematopoietic stem cells show defective interaction with the hematopoietic microenvironment and long-term engraftment failure.Rac2基因缺陷的造血干细胞与造血微环境的相互作用存在缺陷，且长期植入失败。
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