Rac GTPases play multiple roles in erythropoiesis.
作者信息
Ji Peng, Lodish Harvey F
出版信息
Haematologica. 2010 Jan;95(1):2-4. doi: 10.3324/haematol.2009.015511.
Abstract
摘要
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本文引用的文献
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Rac1 and Rac2 GTPases are necessary for early erythropoietic expansion in the bone marrow but not in the spleen.
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2
Mammalian Rho GTPases: new insights into their functions from in vivo studies.
Nat Rev Mol Cell Biol. 2008 Sep;9(9):690-701. doi: 10.1038/nrm2476.
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Enucleation of cultured mouse fetal erythroblasts requires Rac GTPases and mDia2.
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Rac GTPases regulate the morphology and deformability of the erythrocyte cytoskeleton.
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Generation of rac3 null mutant mice: role of Rac3 in Bcr/Abl-caused lymphoblastic leukemia.
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