Department of Cardiology, First Affiliated Hospital, China Medical University, Shenyang, People's Republic of China.
Ann Fam Med. 2010 Jan-Feb;8(1):19-24. doi: 10.1370/afm.1018.
OBJECTIVE We wanted to determine the incidence of hypertension and its risk factors among rural Chinese adults.
A population-based sample of 24,360 rural Chinese adults aged 35 years and older and free from hypertension at baseline was observed from 2004-2006 to 2008. Incident hypertension was defined as a systolic pressure of 140 mm Hg or greater, diastolic pressure of 90 mm Hg or greater, or current use of antihypertensive medication.
During a mean follow-up period of 28 months, 29.6% of men and 23.4% of women developed hypertension. The age-adjusted incidence was higher in men (12.75 per 100 person-years) than in women (10.04 per 100 person-years). Among men, independent predictors of incident hypertension were baseline age (hazard ratio [HR] = 1.11; 95% confidence interval [CI], 1.10-1.13), Mongolian ethnicity (HR = 1.09; 95% CI, 1.01-1.18), use of alcohol, (HR = 1.14; 95% CI, 1.06-1.23), high income vs low income (HR = 1.11; 95% CI, 1.00-1.22; and HR = 1.11; 95% CI, 1.03-1.20), prehypertension vs normotension (HR = 1.18; 95% CI, 1.08-1.28), overweight and obesity (HR = 1.28; 95% CI, 1.17-1.40), baseline salt intake (HR = 1.00; 95% CI, 1.00-1.01) and family history of hypertension (HR = 1.14; 95% CI, 1.03-1.27). With the exception of use of alcohol and mean income, the results were similar for women, except that low physical activity was shown as a risk factors as well. The awareness, treatment, and control rates for newly developed hypertension were 29.9%, 19.5%, and 1.5%, respectively.
These data indicate that the incidence of hypertension is high among these rural Chinese adults and that it is associated with many risk factors. Our findings further suggest that most newly developed hypertension cases are not treated. The increases in hypertension are probably related to rapid social changes in our country and may apply to other areas of the developing world. These findings call for urgent improvements in hypertension prevention and control programs in rural China.
我们旨在确定高血压的发病率及其在中国农村成年人中的危险因素。
2004-2006 年至 2008 年,对 24360 名年龄在 35 岁及以上、基线时无高血压的农村成年人进行了基于人群的样本观察。新发高血压定义为收缩压≥140mmHg,舒张压≥90mmHg,或正在使用降压药物。
在平均 28 个月的随访期间,男性中有 29.6%,女性中有 23.4%发生了高血压。男性的年龄调整发病率(每 100 人年 12.75 例)高于女性(每 100 人年 10.04 例)。在男性中,新发高血压的独立预测因素为基线年龄(危险比[HR] = 1.11;95%置信区间[CI],1.10-1.13)、蒙古族(HR = 1.09;95%CI,1.01-1.18)、饮酒(HR = 1.14;95%CI,1.06-1.23)、高收入与低收入(HR = 1.11;95%CI,1.00-1.22;HR = 1.11;95%CI,1.03-1.20)、高血压前期与正常血压(HR = 1.18;95%CI,1.08-1.28)、超重和肥胖(HR = 1.28;95%CI,1.17-1.40)、基线盐摄入量(HR = 1.00;95%CI,1.00-1.01)和高血压家族史(HR = 1.14;95%CI,1.03-1.27)。除饮酒和平均收入外,女性的结果与之相似,只是低体力活动也被认为是危险因素。新诊断高血压的知晓率、治疗率和控制率分别为 29.9%、19.5%和 1.5%。
这些数据表明,中国农村成年人的高血压发病率较高,与许多危险因素有关。我们的研究结果进一步表明,大多数新发生的高血压病例未得到治疗。高血压的增加可能与我国社会的快速变化有关,可能适用于发展中国家的其他地区。这些发现呼吁迫切需要改善中国农村地区的高血压预防和控制计划。