El-Khuffash Afif, Molloy Eleanor
Department of Neonatology, Hospital for Sick Children, Toronto, ON, Canada M5G 1X8.
Int J Pediatr. 2009;2009:175216. doi: 10.1155/2009/175216. Epub 2009 Dec 30.
The use of natriuretic peptides in the neonatal population is emerging. B-type Natriuretic Peptide (BNP) and N-terminal-Pro-BNP (NTpBNP) are used in the adult population to assess myocardial function and volume loading. Their role in prognosis following cardiac surgery has also been identified. In preterm infants NTpBNP is becoming increasingly recognised as a potential screening tool for patent ductus arteriosus (PDA), and a marker for myocardial performance. In addition, NTpBNP may provide prognostic information in preterm infants and term infants with congenital diaphragmatic hernia (CDH). In this paper, the role of NTpBNP in the preterm population will be discussed.
利钠肽在新生儿群体中的应用正在兴起。B型利钠肽(BNP)和N末端B型利钠肽原(NTpBNP)在成人中用于评估心肌功能和容量负荷。它们在心脏手术后预后中的作用也已得到确认。在早产儿中,NTpBNP越来越被认为是动脉导管未闭(PDA)的潜在筛查工具以及心肌功能的标志物。此外,NTpBNP可能为患有先天性膈疝(CDH)的早产儿和足月儿提供预后信息。本文将讨论NTpBNP在早产儿群体中的作用。