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[苍术的化学、分子生物学及药理学研究进展]

[Advances in chemistry, molecular biology and pharmacological of Cangzhu].

作者信息

Fu Meihong, Zhu Donghai, Fang Jing, Song Hongyue, Yang Bin, Xiong Yulan

机构信息

Institute of Chinese Materia Medica, China Academy of Chinese Medical Sciences, Beijing, China.

出版信息

Zhongguo Zhong Yao Za Zhi. 2009 Oct;34(20):2669-72.

Abstract

We described chemical composition in Cangzhu in recent years, volatile oil is the important chemical composition, The beta-eudesmol, hinesol are active ingredient in volatile oil and there are 38 kind of glycosides. At the same time, we overview the applying of RAPD technology in atractylodes lancea. The results is that there are correlation in chemical composition, genetic differentiation and geographical distribution, there is some truth in bounded by a territorial division of the north-south Cangzhu, and genetic differentiation has been happened in atractylodes lancea to adapting the environment. We described advances of pharmacological in dampness spleen, cardiovascular system, genitourinary system, nervous system, and the results show that there are pharmacological activity in digestive system, cardiovascular system, genitourinary system of atractylodes lancea.

摘要

我们阐述了近年来苍术的化学成分,挥发油是其重要的化学成分,β-桉叶醇、广藿香醇是挥发油中的活性成分,且含有38种糖苷。同时,我们概述了RAPD技术在白术中的应用。结果表明,其化学成分、遗传分化与地理分布之间存在相关性,以南北地域划分苍术有一定道理,白术已发生遗传分化以适应环境。我们阐述了苍术在燥湿健脾、心血管系统、泌尿生殖系统、神经系统方面的药理研究进展,结果表明苍术在消化系统、心血管系统、泌尿生殖系统具有药理活性。

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