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[塞内加尔干燥综合征患者的牙周状况。在内科服务部门进行的一项病例对照研究]

[Periodontal status of Senegalese patients with Sjögren's syndrome. A case control study at the Service of Internal Medicine].

作者信息

Seck-Diallo A, Diallo S, Benoist H M, Diouf A, Sembène M, Diallo P D

机构信息

Sce de parodontologie, Dpt d'Odontologie, Université Cheikh Anta Diop de Dakar, Sénégal.

出版信息

Odontostomatol Trop. 2009 Jun;32(126):39-46.

Abstract

The aim of this study is to compare the periodontal status of patients with Gougerot-Sjögren syndrome (GSS) to healthy subjects in order to investigate the relation between periodontal disease and GSS. To achieve this aim, one hundred and three patients, among whom 36 with primary GSS and 67 with secondary GSS, were selected and compared with one hundred and three (103) control subjects. The hygiene level was evaluated with Silness and Löe plaque index (PI) and inflammation level with Löe and Silness gingival index (GI). Probing depth and clinical attachment loss was measured with Williams periodontal probe. Mean plaque indices were identical for both groups (1.27 +/- 0.1 versus 1.22 +/- 0.1, p = 0.67). Compared with control subjects, the inflammation index scores were significantly higher among SSG patients (IG = 1.1 +/- 0.1 versus 0.44 +/- 0.2, p < 0,001). The logistical regression model applied to the whole sample showed that patients with GSS had a higher risk of developing periodontal disease (IG : OR 5.508, state 95% CI [1.66-9.60] ; PP : OR = 4.51 95% CI [1.692-12.024]). A training program for GSS patients seems essential, in order to manage the deleterious effects of defective oral-dental ground. It would allow convincing patients about the interest of prevention through regular surveillance and care.

摘要

本研究的目的是比较古热罗-舍格伦综合征(GSS)患者与健康受试者的牙周状况,以调查牙周疾病与GSS之间的关系。为实现这一目标,选取了103例患者,其中36例为原发性GSS患者,67例为继发性GSS患者,并与103名对照受试者进行比较。使用西尔斯和勒氏菌斑指数(PI)评估口腔卫生水平,使用勒氏和西尔斯牙龈指数(GI)评估炎症水平。用威廉姆斯牙周探针测量探诊深度和临床附着丧失。两组的平均菌斑指数相同(1.27±0.1对1.22±0.1,p = 0.67)。与对照受试者相比,SSG患者的炎症指数得分显著更高(IG = 1.1±0.1对0.44±0.2,p < 0.001)。应用于整个样本的逻辑回归模型显示,GSS患者患牙周疾病的风险更高(IG:OR 5.508,95%置信区间[1.66 - 9.60];PP:OR = 4.51,95%置信区间[1.692 - 12.024])。为应对口腔牙质缺陷的有害影响,为GSS患者开展培训项目似乎至关重要。这将使患者相信通过定期监测和护理进行预防的益处。

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