实体器官移植受者中的艰难梭菌。
Clostridium difficile in solid organ transplant recipients.
机构信息
Department of Medicine, Washington University School of Medicine, Seattle, WA, USA.
出版信息
Am J Transplant. 2009 Dec;9 Suppl 4(0 4):S35-40. doi: 10.1111/j.1600-6143.2009.02891.x.
Abstract
infection (CDI) is a common problem encountered in solid organ transplant (SOT) recipients and the incidence is increasing. Generally, SOT recipients have an incidence of CDI that is similar to other post-operative patients, but this group has several unique risk factors that may contribute to more severe disease. Recent studies in non-transplant patients have indicated that treatment choices should be based on the severity of the illness. Although there continues to be a lack of well designed, randomized, controlled trials to support the management decisions that must be made for SOT recipients with CDI, the available evidence is reviewed and summarized for these treatment guidelines.
摘要
感染（CDI）是实体器官移植（SOT）受者中常见的问题，其发病率正在增加。一般来说，SOT 受者的 CDI 发病率与其他术后患者相似，但该人群有几个独特的危险因素，可能导致更严重的疾病。最近在非移植患者中的研究表明，治疗选择应基于疾病的严重程度。尽管仍然缺乏精心设计的、随机的、对照试验来支持必须为 CDI 的 SOT 受者做出的管理决策，但为这些治疗指南审查和总结了现有证据。
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