Department of Diagnostic Medical Sciences and Special Therapies, University of Padua Medical School, Padua, Italy.
Cardiovasc Pathol. 2010 May-Jun;19(3):171-82. doi: 10.1016/j.carpath.2009.09.010. Epub 2010 Jan 13.
The role of different types of infections in heart diseases is more important than commonly thought, with new and re-emerging infections (i.e., Mycobacterium tuberculosis). This review addresses the pathology of infective pericarditis, myocarditis, and endocarditis, mainly focusing on the significance of molecular techniques in the detection of infective agents. Molecular investigations represent important ancillary diagnostic tools and combined with other conventional approaches provide a more precise final diagnosis. A close collaboration and communication among cardiologists, cardiac surgeons, pathologists, and microbiologists is essential to ensure optimal diagnoses and management as well as a favorable impact on patient outcome.
不同类型的感染在心脏病中的作用比人们通常认为的更为重要,包括新出现和再现的感染(如结核分枝杆菌)。这篇综述主要讨论了感染性心包炎、心肌炎和心内膜炎的病理学,重点介绍了分子技术在感染因子检测中的意义。分子研究是重要的辅助诊断工具,与其他传统方法相结合,可以提供更准确的最终诊断。心脏病专家、心脏外科医生、病理学家和微生物学家之间的密切合作和沟通对于确保最佳诊断和管理以及对患者预后产生有利影响至关重要。