Neurophysiology Service, Massachusetts General Hospital, MA 02114, USA.
Clin Neurophysiol. 2010 Jul;121(7):998-1006. doi: 10.1016/j.clinph.2009.12.016. Epub 2010 Jan 13.
Propofol is an emulsion formulation of 2,6 diisopropylphenol developed in 1975. Widely recognized, it offers beneficial effects compared with other sedative drugs. Propofol is used in several clinical situations including multiple surgical procedures and critical-care medical conditions. Since technological advances over recent years have allowed an ever-increasing number of patients undergoing propofol therapy to be monitored by using continuous digital EEG, it is important to have a complete understanding of the effects of propofol on EEG in diverse clinical scenarios. This paper presents a review of the effects of propofol in electroencephalograms and discusses proconvulsive, anticonvulsive proprieties and the EEG findings in different medical conditions.
丙泊酚是一种 2,6 二异丙基苯酚的乳剂配方，于 1975 年开发。与其他镇静药物相比，它具有广泛认可的有益作用。丙泊酚用于多种临床情况，包括多种手术和重症监护医疗条件。由于近年来技术进步，越来越多接受丙泊酚治疗的患者可以通过连续数字脑电图进行监测，因此，全面了解丙泊酚在不同临床情况下对脑电图的影响非常重要。本文综述了丙泊酚对脑电图的影响，并讨论了其在不同医疗条件下的致惊厥、抗惊厥特性和脑电图表现。
