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一项关于酒精与抑郁症共病的前瞻性研究。

A prospective study of comorbidity of alcohol and depression.

作者信息

Pradhan S N, Adhikary S R, Sharma S C

机构信息

Department of Psychiatry, Kathmandu Medical College Teaching Hospital, Sinamangal, Nepal.

出版信息

Kathmandu Univ Med J (KUMJ). 2008 Jul-Sep;6(23):340-5. doi: 10.3126/kumj.v6i3.1709.

DOI:10.3126/kumj.v6i3.1709
PMID:20071816
Abstract

OBJECTIVE

The aim of the work was to study the socio-demographic variables and their co-morbidity to alcohol consumption and presence of depressive symptomatology.

DESIGN

This was a prospective cross-sectional study.

MATERIALS AND METHODS

The study was carried out in 53 patients, who were admitted in the wards of Kathmandu Medical College Teaching Hospital (KMCTH) with the diagnosis of mental and behavioural disorder due to the use of alcohol according to ICD-10. The patients were taken from 1st February 2006 to 30th December 2006. All patients were rated using Hamilton Depression Rating Scale (HDRS). Comparison of alcohol intake, depressive symptomatology and their associations with various socio-demographic variables were done using standard statistical procedures.

RESULTS

The present study has shown that more than 94.3% of the patients were suffering from depressive episode. Among all the patients, 11.3% were suffering from severe depressive episode. Alcohol intake was more significantly correlated (p = .002) with Brahmin and Chhetri caste. The other significant correlation of alcohol intake and sociodemographic variable was Nuclear family (p=.001). Among these patients the severity of depression was significantly (p= .001)associated with duration of alcohol intake. Marital status was another important factor affecting comorbidity of alcohol intake and presence of depressive symptoms (p =.002). Students of 10th to 12th grades of school were found to be using alcohol more often (45.3%). Middle socio-economic status (60.4%) was using alcohol more frequently than other socioeconomical classes.

CONCLUSION

Severity of depression and alcohol intake was found to be significantly associated with various socio-demographic variables such as caste, family structure, marital status and educational status.

摘要

目的

本研究旨在探讨社会人口统计学变量及其与酒精消费和抑郁症状的共病情况。

设计

这是一项前瞻性横断面研究。

材料与方法

该研究对53例根据国际疾病分类第10版(ICD - 10)诊断为酒精所致精神和行为障碍的患者进行,这些患者于2006年2月1日至2006年12月31日入住加德满都医学院教学医院(KMCTH)病房。所有患者均使用汉密尔顿抑郁量表(HDRS)进行评分。采用标准统计程序对酒精摄入量、抑郁症状及其与各种社会人口统计学变量的关联进行比较。

结果

本研究表明,超过94.3%的患者患有抑郁发作。在所有患者中,11.3%患有重度抑郁发作。酒精摄入量与婆罗门和切特里种姓的相关性更为显著(p = 0.002)。酒精摄入量与社会人口统计学变量的另一个显著相关性是核心家庭(p = 0.001)。在这些患者中,抑郁的严重程度与酒精摄入持续时间显著相关(p = 0.001)。婚姻状况是影响酒精摄入与抑郁症状共病的另一个重要因素(p = 0.002)。发现10至12年级的学生饮酒更为频繁(45.3%)。中等社会经济地位(60.4%)的人群比其他社会经济阶层饮酒更频繁。

结论

发现抑郁严重程度和酒精摄入量与种姓、家庭结构、婚姻状况和教育状况等各种社会人口统计学变量显著相关。

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