Dhungel K U, Parthasarathy D, Dipali S
Department of Physiology, Nepal Medical College, Kathmandu, Nepal.
Kathmandu Univ Med J (KUMJ). 2008 Jul-Sep;6(23):346-54. doi: 10.3126/kumj.v6i3.1710.
In diagnosis and treatment of respiratory diseases, the assessment of lung functions is of considerable importance. So, normal reference values for pulmonary function tests of any population need to be assessed.
An attempt has been made in the present study to measure the peak expiratory flow rate (PEFR) in healthy Nepalese children and young adults.
One hundred ninety six (196) students were selected by inclusion criteria from different schools and colleges in Pokhara Sub-Metropolitan City, Nepal. The anthropometric measurements and peak expiratory flow rate (PEFR) were measured by standard procedures.
The mean PEFR values of males and females are found to have 350.3 (+/-135.0) l.min-1 and 280.2 (+/-98.77) l. min-1 respectively. The PEFR values of Nepalese males of the present study are found to be higher as compared to their females' counterparts. It is interestingly noted that at preadolescence time, PEFR is almost comparable in both sexes but after puberty males attained significantly higher values than females. The trend of PEFR values with development of the age is also been noted. It is interestingly pointed out that PEFR values of Nepalese males in the present study increases significantly with the advancement of age up to 20 years of age and then after PEFR do not change. On the other hand, females showed significant PEFR increment with the advancement of age up to 15 years of age only and then after PEFR do not improve significantly.
PEFR was found to be influenced significantly by height not by the weight. Finally, a prediction equation was established by which PEFR of Nepalese population of 5 to 25 years of age can be estimated from age or height.
在呼吸系统疾病的诊断和治疗中,肺功能评估具有相当重要的意义。因此,需要评估任何人群肺功能测试的正常参考值。
本研究试图测量健康尼泊尔儿童和青年的呼气峰值流速(PEFR)。
根据纳入标准,从尼泊尔博卡拉市不同学校和学院选取了196名学生。通过标准程序测量人体测量指标和呼气峰值流速(PEFR)。
发现男性和女性的平均PEFR值分别为350.3(±135.0)升/分钟和280.2(±98.77)升/分钟。本研究中尼泊尔男性的PEFR值高于女性。有趣的是,在青春期前,男女的PEFR几乎相当,但青春期后男性的值明显高于女性。还注意到PEFR值随年龄增长的趋势。有趣的是指出,本研究中尼泊尔男性的PEFR值在20岁之前随年龄增长显著增加,之后不再变化。另一方面,女性仅在15岁之前随年龄增长PEFR有显著增加,之后PEFR没有显著改善。
发现PEFR受身高显著影响,而非体重。最后,建立了一个预测方程,可根据年龄或身高估算5至25岁尼泊尔人群的PEFR。