泰国儿童呼气峰值流速的参考值。

The reference values of peak expiratory flow rate in Thailand children.

作者信息

Srisingh Klaita, Phuaksaman Chutima

机构信息

Department of Pediatrics, Faculty of Medicine, Naresuan University, Phitsanulok, Thailand.

出版信息

J Thorac Dis. 2021 Jan;13(1):31-38. doi: 10.21037/jtd-20-1846.

DOI:10.21037/jtd-20-1846

PMID:33569182

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7867850/

Abstract

BACKGROUND

Daily evaluation of peak expiratory flow rate (PEFR) is quite useful for monitoring and adjusting an asthmatic patient's treatment. Many factors including geography, ethnicity, socio-economic conditions, gender, and anthropometric play a role in lung function differences studies have found. The aim of this study is to present normal PEFR and to establish a PEFR equation for Thai children living in a suburban environment.

METHODS

This study includes a cross-section of healthy children aged 6 to 18. It was conducted in Phitsanulok Province in the lower north of Thailand. The children were chosen to participate from five primary and secondary schools over the period from February 2014 to January 2015. The children were instructed on how to use the Wright peak flow meter (Clement Clarke International Ltd.). All of the participants performed PEFR 3 times and the highest value was recorded.

RESULTS

A total of 2,000 students were initially examined; 80 students were excluded from the study. A total of 1,920 healthy children were recruited between the ages of 6 and18 years. Among them, 719 (37.4%) were males and 1,201 (62.6%) were females. The median age was 18 [12-18] years old, mean height, weight, body mass index (BMI) and PEFR were 155.98±14.99 cm, 51.38±16.95 kg, 20.62±4.79 kg/m and 339.31±113.55 L/min, respectively. PEFR has a linear relationship in regards age, weight, height and BMI. For males, age was the strongest factor associated with PEFR (r=0.838, P<0.001). Females had a highly significant correlation between height and PEFR (r=0.532, P<0.001). The regression equations are PEFR = (1.34 × height) + (1.41 × weight) + (16.56 × age) - 137.88 for males (R=0.751, P<0.001) and PEFR = (1.31 × height) + (0.94 × weight) + (7.30 × age) - 55.27 for females (R=0.507, P<0.001).

CONCLUSIONS

This research study has provided the normal range of PEFR for Thai children aged from 6 to 18 years in Phitsanulok. The data was obtained using the Wright peak flow meter. Height, weight, and age were the significant determiners of the PEFR for each sex in the regression equation.

摘要

背景

每日评估呼气峰值流速（PEFR）对于监测和调整哮喘患者的治疗非常有用。研究发现，包括地理位置、种族、社会经济状况、性别和人体测量学等在内的许多因素在肺功能差异中起作用。本研究的目的是呈现泰国郊区儿童的正常PEFR，并建立PEFR方程。

方法

本研究纳入了6至18岁的健康儿童横断面。研究在泰国北部下游的彭世洛府进行。2014年2月至2015年1月期间，从五所中小学中挑选儿童参与研究。指导儿童如何使用赖特峰值流量计（克莱门特·克拉克国际有限公司）。所有参与者进行3次PEFR测量，并记录最高值。

结果

最初共检查了2000名学生；80名学生被排除在研究之外。共招募了1920名6至18岁的健康儿童。其中，男性719名（37.4%），女性1201名（62.6%）。中位年龄为18[12 - 18]岁，平均身高、体重、体重指数（BMI）和PEFR分别为155.98±14.99厘米、51.38±16.95千克、20.62±4.79千克/平方米和339.31±113.55升/分钟。PEFR与年龄、体重、身高和BMI呈线性关系。对于男性，年龄是与PEFR相关的最强因素（r = 0.838，P < 0.001）。女性身高与PEFR之间存在高度显著的相关性（r = 0.532，P < 0.001）。回归方程为男性：PEFR =（1.34×身高）+（1.41×体重）+（16.56×年龄）- 137.88（R = 0.751，P < 0.001）；女性：PEFR =（1.31×身高）+（0.94×体重）+（7.30×年龄）- 55.27（R = 0.507，P < 0.001）。