伊朗南部年轻和老年患者头颈部鳞状细胞癌的社会人口统计学和病因学差异

Sociodemographic and etiological differences of head and neck squamous cell carcinoma in young and old patients in southern Iran.

作者信息

Andisheh-Tadbir Azadeh, Mehrabani Davood, Heydari Seyed Taghi

机构信息

Department of Oral Pathology, School of Dentistry, Fars Cancer Registry Center, Nemazee Hospital, Shiraz University of Medical Sciences, Shiraz, Iran.

出版信息

J Craniofac Surg. 2010 Jan;21(1):126-8. doi: 10.1097/SCS.0b013e3181c46c10.

DOI:10.1097/SCS.0b013e3181c46c10

PMID:20072017

Abstract

Head and neck squamous cell carcinoma (HNSCC) is typically seen in middle-aged to elderly men but, recently, is increasing in young adults. The aim of this study was to compare the demographic and etiological data of young and old patients with HNSCC in southern Iran. Patients with HNSCC were divided into 2 groups: the young (<or=40 y old) and the old (>or=50 y old). Both groups showed male predilection. The nasopharynx was the most common site in the young group (68.5%), whereas the oral cavity (40%) was the most common site in the old group. In the young group, 68.4% showed none of the usual risk factors. The results suggest that factors other than tobacco and alcohol may be implicated in the development of HNSCC in young patients in southern Iran.

摘要

头颈部鳞状细胞癌（HNSCC）通常见于中老年男性，但近年来在年轻成年人中的发病率呈上升趋势。本研究旨在比较伊朗南部年轻和老年HNSCC患者的人口统计学和病因学数据。HNSCC患者分为两组：年轻组（≤40岁）和老年组（≥50岁）。两组均以男性为主。鼻咽是年轻组最常见的部位（68.5%），而口腔（40%）是老年组最常见的部位。在年轻组中，68.4%的患者未显示出任何常见的危险因素。结果表明，在伊朗南部年轻患者中，除烟草和酒精外的其他因素可能与HNSCC的发生有关。