Department of Otorhinolaryngology, The Catholic University of Korea School of Medicine, Seoul, Korea.
Clin Exp Otorhinolaryngol. 2009 Dec;2(4):198-202. doi: 10.3342/ceo.2009.2.4.198. Epub 2009 Dec 31.
Myeloid sarcoma is a rare condition that's caused by the aggregation of immature myeloid cells in leukemic patients. Myeloid sarcoma occurring in the temporal bone more frequently involves the mastoid bone than is the case for metastatic lesions arising from non-systemic malignancies. The disease is difficult to diagnose when it presents with symptoms that mimic otomastoiditis. However, an early diagnosis is important in order to achieve complete remission of the disease. Magnetic resonance imaging of the temporal bone is useful for making the diagnosis of myeloid sarcoma, and especially to evaluate the extent of disease. High-dose radio- or chemotherapies are the first-line approaches and possibly the only approaches to achieve complete remission and to cure the disease. With the aim of improving our understanding of myeloid sarcoma in the temporal bone, the present report describes our experience with 5 such cases and we compare the clinical features of these 5 patients with those clinical features of patients who have metastatic lesions.
骨髓肉瘤是一种罕见的病症，由白血病患者中未成熟髓细胞的聚集引起。发生在颞骨的骨髓肉瘤比非系统性恶性肿瘤转移病变更常累及乳突骨。当疾病表现出类似于乳突炎的症状时，诊断较为困难。然而，早期诊断对于实现疾病的完全缓解非常重要。颞骨磁共振成像有助于诊断骨髓肉瘤，特别是评估疾病的范围。高剂量的放化疗是一线治疗方法，可能是实现完全缓解和治愈疾病的唯一方法。为了提高我们对颞骨骨髓肉瘤的认识，本报告描述了我们对 5 例此类病例的经验，并将这 5 例患者的临床特征与患有转移病变的患者的临床特征进行了比较。
