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PREPARATION OF (S)-tert-ButylPHOX (Oxazole, 4-(1,1-dimethylethyl)-2-[2-(diphenylphosphino)phenyl]-4,5-dihydro- (4S)-).

作者信息

Krout Michael R, Mohr Justin T, Stoltz Brian M

出版信息

Organic Synth. 2009 Jan 1;86:181. doi: 10.15227/orgsyn.086.0181.

DOI:10.15227/orgsyn.086.0181
PMID:20072718
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2805096/
Abstract
摘要

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PREPARATION OF (S)-tert-ButylPHOX (Oxazole, 4-(1,1-dimethylethyl)-2-[2-(diphenylphosphino)phenyl]-4,5-dihydro- (4S)-).（S）-叔丁基PHOX（恶唑，4-（1,1-二甲基乙基）-2-[2-（二苯基膦基）苯基]-4,5-二氢-（4S）-）的制备
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本文引用的文献

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Homogeneous pd-catalyzed enantioselective decarboxylative protonation.均相钯催化对映选择性脱羧质子化反应
Org Lett. 2008 Mar 20;10(6):1039-42. doi: 10.1021/ol702821j. Epub 2008 Feb 28.
2
Rhodium-catalyzed enantioselective desymmetrization of meso-3,5-dimethyl glutaric anhydride: a general strategy to syn-deoxypolypropionate synthons.铑催化内消旋3,5-二甲基戊二酸酐的对映选择性去对称化：合成顺式脱氧聚丙酸酯合成子的通用策略。
J Am Chem Soc. 2007 Aug 1;129(30):9302-3. doi: 10.1021/ja073269s. Epub 2007 Jul 10.
3
A facile and modular synthesis of phosphinooxazoline ligands.膦基恶唑啉配体的简便模块化合成。
Org Lett. 2007 Jun 21;9(13):2529-31. doi: 10.1021/ol070884s. Epub 2007 May 31.
4
Catalytic enantioselective decarboxylative protonation.催化对映选择性脱羧质子化反应
J Am Chem Soc. 2006 Sep 6;128(35):11348-9. doi: 10.1021/ja063335a.
5
Deracemization of quaternary stereocenters by Pd-catalyzed enantioconvergent decarboxylative allylation of racemic beta-ketoesters.通过钯催化外消旋β-酮酯的对映汇聚脱羧烯丙基化反应实现季碳立体中心的去消旋化
Angew Chem Int Ed Engl. 2005 Oct 28;44(42):6924-7. doi: 10.1002/anie.200502018.
6
Catalytic asymmetric hydrogenation of N-iminopyridinium ylides: expedient approach to enantioenriched substituted piperidine derivatives.N-亚氨基吡啶叶立德的催化不对称氢化：对映体富集的取代哌啶衍生物的便捷合成方法
J Am Chem Soc. 2005 Jun 29;127(25):8966-7. doi: 10.1021/ja0525298.
7
The enantioselective Tsuji allylation.对映选择性的辻烯丙基化反应。
J Am Chem Soc. 2004 Nov 24;126(46):15044-5. doi: 10.1021/ja044812x.
8
Copper-catalyzed C-P bond construction via direct coupling of secondary phosphines and phosphites with aryl and vinyl halides.通过仲膦和亚磷酸酯与芳基卤化物和乙烯基卤化物的直接偶联实现铜催化的C-P键构建。
Org Lett. 2003 Jun 26;5(13):2315-8. doi: 10.1021/ol0346640.
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Synthesis of amino acid derivatives via enantio- and diastereoselective Pd-catalyzed allylic substitutions with a non-stabilized enolate as nucleophile.通过以非稳定烯醇盐为亲核试剂的对映选择性和非对映选择性钯催化烯丙基取代反应合成氨基酸衍生物。
Chem Commun (Camb). 2002 Jun 21(12):1270-1. doi: 10.1039/b203791m.
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Catalytic enantioselective aza-Diels-alder reactions of imines--an approach to optically active nonproteinogenic alpha-amino acids.亚胺的催化对映选择性氮杂狄尔斯-阿尔德反应——一种合成光学活性非蛋白质ogenicα-氨基酸的方法。
Chemistry. 2000 Jul 3;6(13):2435-48. doi: 10.1002/1521-3765(20000703)6:13<2435::aid-chem2435>3.0.co;2-z.