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[中药按摩对更年期综合征女性内分泌功能的影响]

[Effect of Chinese medicinal massage on endocrinal function in women with climacteric syndrome].

作者信息

Jin Tao, Han Li-Juan, Shen Yan-Hong

机构信息

Beijing Massage Hospital, Beijing, China.

出版信息

Zhongguo Zhong Xi Yi Jie He Za Zhi. 2009 Oct;29(10):875-8.

Abstract

OBJECTIVE

To explore the therapeutic effect of Chinese medicinal massage with nourishing-Shen and activating-blood manipulation in treating women with climacteric syndrome and its influence on endocrinal function.

METHODS

Sixty patients were assigned to two groups, the 40 patients in the treated group were treated by Chinese medicinal massage for 20 min once every other day; the 20 patients in the control group were treated by hormone replacement therapy with Premarin 0.625 g, once daily by oral taking. The therapeutic efficacy was evaluated after two-month treatment by changes of serum levels of estradiol (E2), follicular stimulating hormone (FSH), luteinizing hormone (LH), and Kupperman index before and after treatment.

RESULTS

Kupperman index showed that the total symptom score in the treated group was improved from 30.71 +/- 8.43 scores before treatment to 8.21 +/- 5.14 scores after treatment, with a decrement of 22.50 +/- 8.14 scores, which was higher than that in the control group, from 24.32 +/- 5.44 scores to 5.92 +/- 3.58 scores, with a decrement of 18.40 +/- 4.50 scores, the difference between them was statistically significant (t = 2.52, P = 0.014). The serum level of E2 increased in both groups significantly after treatment, from 20.23 +/- 20.78 ng/L to 54.34 +/- 24.26 ng/L in the treated group (t= -2.73, P = 0.006), and from 16.15 +/- 24.40 ng/L to 40.61 +/- 81.54 ng/L in the control group (t = -1.72, P = 0.086), but the difference between groups was statistical insignificant (t= -1.120, P = 0.263). As for levels of FSH and LH, their decrements in the control group (13.16 +/- 11.29 mlU/mL and 10.37 +/- 9.21 mlU/mL) were larger than those in the treated group (4.92 +/- 4.26 mlU/mL and 0.17 +/- 2.42 mlU/mL), respectively (t = - 2.49, P = 0.013; t = - 2.38, P = 0.017).

CONCLUSION

Chinese medicinal massage manipulation could improve the Kupperman index of all the 13 symptoms in women with climacteric syndrome, and increase the E2 level in serum.

摘要

目的

探讨补肾活血推拿法治疗更年期综合征的疗效及其对内分泌功能的影响。

方法

将60例患者分为两组,治疗组40例采用中药推拿治疗,每两日1次,每次20分钟;对照组20例采用激素替代疗法,口服倍美力0.625g,每日1次。治疗两个月后,根据治疗前后血清雌二醇(E2)、卵泡刺激素(FSH)、黄体生成素(LH)水平及Kupperman指数的变化评价疗效。

结果

Kupperman指数显示,治疗组总症状评分由治疗前的30.71±8.43分降至治疗后的8.21±5.14分,下降了22.50±8.14分,高于对照组(由24.32±5.44分降至5.92±3.58分,下降了18.40±4.50分),两组差异有统计学意义(t = 2.52,P = 0.014)。两组治疗后血清E2水平均显著升高,治疗组由20.23±20.78ng/L升至54.34±24.26ng/L(t = -2.73,P = 0.006),对照组由16.15±24.40ng/L升至40.61±81.54ng/L(t = -1.72,P = 0.086),但组间差异无统计学意义(t = -1.120,P = 0.263)。FSH和LH水平方面,对照组下降幅度(分别为13.16±11.29mIU/mL和10.37±9.21mIU/mL)大于治疗组(分别为4.92±4.26mIU/mL和0.17±2.42mIU/mL)(t = -2.49,P = 0.013;t = -2.38,P = 0.017)。

结论

补肾活血推拿法可改善更年期综合征患者13项症状的Kupperman指数,并提高血清E2水平。

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