Pérez-Vega Jorge Humberto, López-Moreno Carmina Yanett, López-Valenzuela José Angel, Rendón-Maldonado José Guadalupe, López-Moreno Héctor Samuel
Facultad de Ciencias Químico-Biológicas, Universidad Autónoma de Sinaloa, Culiacán, Sinaloa, México.
Gac Med Mex. 2009 Sep-Oct;145(5):433-5.
Leishmanisis is a parasitic diseases caused by intracellular protozoan of Leishmania genus. These parasites are transmitted by the bite of phlebotomine flies. Leishmanises are classified in different clinic variants: cutaneous localized or diffuse, mucocutaneous and visceral. In Mexico, the leishmanisis are distributed in several states, however Durango was considered free of leishmaniasis.
A 9 year old male patient with an ulcerated pruriginous node of circular shape, 13 x 18 mm diameter, localized in the back of the right arm with 6 months progression. The patient was a permanent resident of Durango, Mexico. Histopathology evidenced macrophages infected with amastigotes. The PCR-RFLP result was consistent with Leishmania mexicana. Treatment with glucantime was satisfactory.
Here we report the first clinical case of leishmanisis cutaneous localized caused by Leishmania mexicana from Durango, Mexico in a 9 years old male, confirming the increasing propagation of this protozoan parasite in Mexico.
利什曼病是由利什曼原虫属细胞内原生动物引起的寄生虫病。这些寄生虫通过白蛉叮咬传播。利什曼病分为不同的临床类型：皮肤局限性或弥漫性、黏膜皮肤型和内脏型。在墨西哥，利什曼病分布于多个州，然而杜兰戈州曾被认为没有利什曼病。
一名9岁男性患者，右臂背部有一个直径为13×18毫米的圆形溃疡瘙痒结节，病程6个月。该患者是墨西哥杜兰戈州的常住居民。组织病理学证实巨噬细胞感染了无鞭毛体。聚合酶链反应-限制性片段长度多态性（PCR-RFLP）结果与墨西哥利什曼原虫一致。使用葡糖胺治疗效果良好。
在此我们报告了墨西哥杜兰戈州首例由墨西哥利什曼原虫引起的9岁男性皮肤局限性利什曼病临床病例，证实了这种原生动物寄生虫在墨西哥的传播日益增加。
