Tuon Felipe Francisco, Sabbaga Amato Valdir, Floeter-Winter Lucile Maria, de Andrade Zampieri Ricardo, Amato Neto Vicente, Siqueira França Francisco Oscar, Shikanai-Yasuda Maria Aparecida
Infectious and Parasitic Diseases Clinic, Hospital das Clínicas, Faculdade de Medicina da Universidade de São Paulo, Brazil.
Int J Dermatol. 2007 Jun;46(6):628-30. doi: 10.1111/j.1365-4632.2006.03096.x.
American tegumentary leishmaniasis (ATL), an endemic anthropozoonosis in various countries in the world, is caused by parasites of the genus Leishmania. Despite reports on ATL reactivation as a result of immunosuppression, to the best of our knowledge, this paper describes the first case of ATL reactivation in its localized form (cutaneous leishmaniasis) associated with the administration of systemic corticosteroids. The possible action of corticosteroids on the host immune response to the parasite in patients with localized cutaneous leishmaniasis is discussed. This report demonstrates the possibility of ATL reactivation in patients using corticosteroids, an observation that should be considered in individuals treated with this medication.
美洲皮肤利什曼病（ATL）是一种在世界各国流行的人兽共患病，由利什曼原虫属的寄生虫引起。尽管有关于免疫抑制导致ATL复发的报道，但据我们所知，本文描述了首例与全身使用糖皮质激素相关的局限性（皮肤利什曼病）ATL复发病例。讨论了糖皮质激素对局限性皮肤利什曼病患者宿主对寄生虫免疫反应的可能作用。本报告证明了使用糖皮质激素的患者存在ATL复发的可能性，这一观察结果应在接受该药物治疗的个体中予以考虑。
