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子宫次全切除术和全子宫切除术 1 年后的心理健康随访——一项随机研究。

A 1-year follow up of psychological wellbeing after subtotal and total hysterectomy--a randomised study.

机构信息

Department of Obstetrics and Gynaecology, University Hospital, Uppsala, Sweden.

出版信息

BJOG. 2010 Mar;117(4):479-87. doi: 10.1111/j.1471-0528.2009.02467.x. Epub 2010 Jan 14.

Abstract

OBJECTIVE

To compare subtotal abdominal hysterectomy (SH) and total abdominal hysterectomy (TH) regarding influence on postoperative psychological wellbeing and surgical outcome measurements.

DESIGN

A prospective, open, randomised multicentre trial.

SETTING

Seven hospitals and one private clinic in the south-east of Sweden.

POPULATION

Two-hundred women scheduled for abdominal hysterectomy for benign conditions were enrolled in the study; 179 women completed the study (94 SH and 85 TH).

METHODS

Four different psychometric tests were used to measure general wellbeing, depression and anxiety preoperatively, and at 6 and 12 months postoperatively. Statistical analysis of variance and covariance were used.

MAIN OUTCOME MEASURES

Effects of operating method on psychological wellbeing postoperatively. Analysis of demographic, clinical and surgical data, including peri- and postoperative complications and complaints at follow up.

RESULTS

No significant differences were observed between the two groups in any of the psychometric tests. Both surgical methods were associated with a significantly higher degree of psychological wellbeing at 6 and 12 months postoperatively, compared with preoperatively. No significant differences were found in the clinical measures including complications. A substantial number of women experienced persistent cyclic vaginal bleedings after SH. Neither minor or major postoperative complications, nor serum concentration of sex hormones, were associated with general psychological wellbeing 12 months after the operation.

CONCLUSIONS

General psychological wellbeing is equally improved after both SH and TH within 12 months of the operation, and does not seem to be associated with the occurrence of peroperative complications or serum concentration of sex hormones.

摘要

目的

比较次全子宫切除术(SH)和全子宫切除术(TH)对术后心理幸福感和手术结果测量的影响。

设计

前瞻性、开放、随机多中心试验。

地点

瑞典东南部的七家医院和一家私人诊所。

人群

200 名因良性疾病接受腹部子宫切除术的妇女被纳入研究;179 名妇女完成了研究(94 名 SH 和 85 名 TH)。

方法

使用四种不同的心理测试术前、术后 6 个月和 12 个月测量一般幸福感、抑郁和焦虑。使用方差分析和协方差进行统计分析。

主要观察指标

手术方法对术后心理幸福感的影响。分析人口统计学、临床和手术数据,包括围手术期并发症和随访时的投诉。

结果

两组在任何心理测试中均无显著差异。与术前相比,两种手术方法在术后 6 个月和 12 个月时均显著提高了心理幸福感。在包括并发症在内的临床测量中没有发现显著差异。相当数量的妇女在 SH 后出现持续周期性阴道出血。术后 12 个月,轻微或严重的术后并发症以及性激素血清浓度与一般心理幸福感均无相关性。

结论

在手术 12 个月内,SH 和 TH 均可同等程度地改善整体心理幸福感,且似乎与术中并发症的发生或性激素的血清浓度无关。

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