血清果糖胺并非妊娠期糖尿病的有效筛查试验。

Serum fructosamine is not a useful screening test for gestational diabetes.

作者信息

Corcoy R, Cerqueira M J, Pedreño J, Matas J, Codina M, Pou J M, de Leiva A, Cabero L

机构信息

Service of Endocrinology and Nutrition, Hospital de la Santa Creu i Sant Pau, Universitat Autònoma de Barcelona, Spain.

出版信息

Eur J Obstet Gynecol Reprod Biol. 1991 Feb 25;38(3):217-20. doi: 10.1016/0028-2243(91)90295-v.

DOI:10.1016/0028-2243(91)90295-v

PMID:2007448

Abstract

Serum fructosamine was measured in 569 samples of pregnant women without gestational diabetes. We defined abnormal fructosamine as mean + 2SD, and analysed its potential value to detect patients with gestational diabetes diagnosed with current screening criteria. We found serum fructosamine to be an insensitive parameter: Measured at the time of a positive 50 g glucose screening, SF would have detected 4/48 gestational diabetes.

摘要

对569例无妊娠糖尿病的孕妇样本进行了血清果糖胺检测。我们将异常果糖胺定义为均值加2个标准差，并分析了其在按照当前筛查标准诊断妊娠糖尿病患者时的潜在价值。我们发现血清果糖胺是一个不敏感的参数：在50克葡萄糖筛查呈阳性时进行检测，血清果糖胺仅能检测出4/48例妊娠糖尿病患者。