Roberts A B, Baker J R, Metcalf P, Mullard C
Department of Obstetrics, National Women's Hospital, Auckland, New Zealand.
Obstet Gynecol. 1990 Nov;76(5 Pt 1):773-5. doi: 10.1097/00006250-199011000-00009.
Five hundred seven women were screened for gestational diabetes between 20-36 weeks' gestation. All received a 100-g glucose (polycose) load at 28 weeks with measurement of plasma glucose 1 hour later. Fructosamine levels were measured at 4-week intervals from 20-36 weeks. At 36 weeks, a full 100-g 3-hour glucose tolerance test was performed on all subjects. Eighteen women were diagnosed as having gestational diabetes. The glucose load had a sensitivity of 81% in detection of gestational diabetes, compared with 50% for fructosamine at 36 weeks. Fructosamine is not useful as a screening test for gestational diabetes as currently defined.
对507名妊娠20至36周的女性进行了妊娠期糖尿病筛查。所有女性在孕28周时均接受了100克葡萄糖（多聚葡萄糖）负荷试验，并于1小时后测定血糖。从孕20周开始，每隔4周测量一次糖化血清蛋白水平。孕36周时，对所有受试者进行了完整的100克3小时葡萄糖耐量试验。18名女性被诊断为患有妊娠期糖尿病。葡萄糖负荷试验检测妊娠期糖尿病的敏感性为81%，而36周时糖化血清蛋白的敏感性为50%。糖化血清蛋白作为目前定义的妊娠期糖尿病筛查试验并无用处。
