Signalling Programme, Babraham Institute, Cambridge, UK.
FEBS Lett. 2010 Apr 2;584(7):1302-12. doi: 10.1016/j.febslet.2010.01.011. Epub 2010 Jan 13.
The simple phosphoinositide phosphatidylinositol 3-phosphate (PI(3)P) has been known to have important functions in endocytic and phagocytic traffic, and to be required for the autophagic pathway. In all of these settings, PI(3)P appears to create platforms that serve to recruit specific effectors for membrane trafficking events. In autophagy, PI(3)P may form the platform for autophagosome biogenesis.
简单的磷酸肌醇磷脂酰肌醇 3-磷酸 (PI(3)P) 已知在胞吞作用和吞噬作用中有重要功能，并且是自噬途径所必需的。在所有这些情况下，PI(3)P 似乎形成了用于招募膜运输事件特定效应物的平台。在自噬中，PI(3)P 可能为自噬体生物发生形成平台。
