Chang Chih-Ching, Tsai Shang-Shyue, Ho Shu-Chen, Yang Chun-Yuh
Institute of Public Health, Kaohsiung Medical University, 100 Shin-Chuan 1st Road, Kaohsiung 80708, Taiwan.
Environ Res. 2005 May;98(1):114-9. doi: 10.1016/j.envres.2004.07.005.
This study was undertaken to determine whether there is an association between air pollutants levels and hospital admissions for cardiovascular diseases (CVD) in Taipei, Taiwan. Hospital admissions for CVD and ambient air pollution data for Taipei were obtained for the period 1997-2001. The relative risk of hospital admission was estimated using a case-crossover approach, controlling for weather variables, day of the week, seasonality, and long-term time trends. For the one-pollutant models, on warm days (>or=20 degrees C) statistically significant positive associations were found between levels of particulate matter <10-microm aerodynamic diameter (PM10), nitrogen dioxide (NO2), carbon monoxide (CO), and ozone (O3). On cool days (<20 degrees C), all pollutants except O3 and SO2 were significantly associated with CVD admissions. For the two-pollutant models, CO, NO2, and O3 were significant in combination with each of the other four pollutants on warm days. On cool days, PM10 remained statistically significant in all the two-pollutant models. This study provides evidence that higher levels of ambient pollutants increase the risk of hospital admissions for CVD.
本研究旨在确定台湾台北市空气污染物水平与心血管疾病(CVD)住院人数之间是否存在关联。获取了1997 - 2001年期间台北市心血管疾病住院人数及环境空气污染数据。采用病例交叉法估计住院风险,并对天气变量、星期几、季节性和长期时间趋势进行了控制。对于单污染物模型,在温暖天气(≥20℃)下,发现空气动力学直径<10微米的颗粒物(PM10)、二氧化氮(NO2)、一氧化碳(CO)和臭氧(O3)水平之间存在统计学显著的正相关。在凉爽天气(<20℃)下,除O3和SO2外,所有污染物均与心血管疾病住院人数显著相关。对于双污染物模型,在温暖天气下,CO、NO2和O3与其他四种污染物中的每一种组合时均具有显著性。在凉爽天气下,PM10在所有双污染物模型中均保持统计学显著性。本研究提供了证据表明环境污染物水平升高会增加心血管疾病住院风险。