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Now there are many (stages) where before there was one: In search of a pathophysiological classification of cirrhosis.

作者信息

Garcia-Tsao Guadalupe, Friedman Scott, Iredale John, Pinzani Massimo

机构信息

Section of Digestive Diseases, Yale University School of Medicine, VA Connecticut Healthcare System, New Haven, CT, USA.

出版信息

Hepatology. 2010 Apr;51(4):1445-9. doi: 10.1002/hep.23478.

DOI:10.1002/hep.23478
PMID:20077563
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2882065/
Abstract
摘要

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Now there are many (stages) where before there was one: In search of a pathophysiological classification of cirrhosis.现在存在许多(阶段),而以前只有一个:寻找肝硬化的病理生理分类。
Hepatology. 2010 Apr;51(4):1445-9. doi: 10.1002/hep.23478.
2
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Hepatic venous pressure gradient predicts development of hepatocellular carcinoma independently of severity of cirrhosis.肝静脉压力梯度可独立于肝硬化严重程度预测肝细胞癌的发生。
J Hepatol. 2009 May;50(5):923-8. doi: 10.1016/j.jhep.2009.01.014. Epub 2009 Mar 5.
2
Angiogenesis in liver disease.肝脏疾病中的血管生成
J Hepatol. 2009 Mar;50(3):604-20. doi: 10.1016/j.jhep.2008.12.011. Epub 2008 Dec 31.
3
Beneficial effects of sorafenib on splanchnic, intrahepatic, and portocollateral circulations in portal hypertensive and cirrhotic rats.
肝纤维化的精准细胞治疗:内皮细胞和巨噬细胞治疗
ILIVER. 2022 Nov 19;1(4):265-274. doi: 10.1016/j.iliver.2022.11.002. eCollection 2022 Dec.
4
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Liver Int. 2025 Jul;45(7):e70166. doi: 10.1111/liv.70166.
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AI-Cirrhosis-ECG (ACE) score for predicting decompensation and liver outcomes.用于预测失代偿和肝脏预后的人工智能-肝硬化-心电图(ACE)评分
JHEP Rep. 2025 Feb 19;7(5):101356. doi: 10.1016/j.jhepr.2025.101356. eCollection 2025 May.
6
Disease trajectory and competing risks of patients with cirrhosis in the US.美国肝硬化患者的疾病轨迹和竞争风险。
PLoS One. 2025 Feb 14;20(2):e0313152. doi: 10.1371/journal.pone.0313152. eCollection 2025.
7
Immunosuppressive treatment in autoimmune decompensated cirrhosis, when to say enough: A retrospective analysis.自身免疫性失代偿期肝硬化的免疫抑制治疗,何时应适可而止:一项回顾性分析。
Medicine (Baltimore). 2025 Feb 7;104(6):e41378. doi: 10.1097/MD.0000000000041378.
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Advanced glycation end products and risk of mortality in patients with cirrhosis: a prospective cohort study.晚期糖基化终末产物与肝硬化患者的死亡风险:一项前瞻性队列研究。
Sci Rep. 2025 Feb 8;15(1):4798. doi: 10.1038/s41598-025-89433-y.
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索拉非尼对门静脉高压和肝硬化大鼠内脏、肝内及门体侧支循环的有益作用。
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Elastography for the non-invasive assessment of liver disease: limitations and future developments.用于肝脏疾病无创评估的弹性成像:局限性与未来发展
Gut. 2009 Feb;58(2):157-60. doi: 10.1136/gut.2008.156489.
5
Mechanisms of hepatic fibrogenesis.肝纤维化形成机制。
Gastroenterology. 2008 May;134(6):1655-69. doi: 10.1053/j.gastro.2008.03.003.
6
Hepatic venous pressure gradient predicts clinical decompensation in patients with compensated cirrhosis.肝静脉压力梯度可预测代偿期肝硬化患者的临床失代偿情况。
Gastroenterology. 2007 Aug;133(2):481-8. doi: 10.1053/j.gastro.2007.05.024. Epub 2007 May 21.
7
Transient elastography for diagnosis of portal hypertension in liver cirrhosis: is there still a role for hepatic venous pressure gradient measurement?瞬时弹性成像在肝硬化门静脉高压诊断中的应用:肝静脉压力梯度测量是否仍有作用?
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