Department of Surgery, Ohta Nishinouchi Hospital, Koriyama, Japan.
Dig Endosc. 2010 Jan;22(1):10-6. doi: 10.1111/j.1443-1661.2009.00931.x.
The endocytoscopy system (ECS), adapted for clinical use in 2003, is an ultra-high-power magnifying endoscope that allows observations at the cell level. ECS is based on the technology of light-contact microscopy. The most evident use of ECS is for real-time, high-resolution diagnosis of nuclear abnormalities, mainly in patients with esophageal cancer. Up to now, three different types of ECS have been available. This diagnostic tool makes it possible to omit histological examination of biopsy samples in approximately 84% of esophageal squamous cell carcinoma, as evidence for both an increase of cell density and nuclear abnormalities is considered to be convincing proof that a lesion is malignant. Here we describe the features of ECS and the background that led to its development, and review the published literature pertaining to the observation of esophageal neoplasms using ECS.
内镜细胞采集系统（endocytoscopy system，ECS）于 2003 年被应用于临床，它是一种超高清放大内镜，可实现细胞级别的观察。ECS 基于光接触显微镜技术。其最明显的用途是实时、高分辨率诊断核异常，主要用于食管癌患者。到目前为止，已经有三种不同类型的 ECS 可供使用。这种诊断工具使得大约 84%的食管鳞状细胞癌患者可以避免进行活检样本的组织学检查，因为细胞密度增加和核异常的证据被认为是病变恶性的有力证据。本文将介绍 ECS 的特点及其发展背景，并对使用 ECS 观察食管肿瘤的相关文献进行综述。
