Department of Neurosurgery, Gulhane Military Medical Academy, Haydarpaşa Eğitim Hastanesi, Nöroşirürji Servisi, 34668 Usküdar, Istanbul, Turkey.
J Clin Neurosci. 2010 Mar;17(3):380-2. doi: 10.1016/j.jocn.2009.02.014. Epub 2010 Jan 15.
Intracranial marginal zone B-cell lymphoma presenting as a dural-based mass is rare. A 45-year-old woman who had generalized tonic-clonic seizures and speech disturbance for 6 months was referred to our hospital. Radiology suggested a subdural hematoma (SDH). No improvement in the radiological findings or symptoms occurred with conservative follow-up. Therefore, she underwent a craniotomy for drainage of the suspected SDH. Intraoperatively, dural plaque-like thickening was observed, with no SDH, and a biopsy was performed. After histopathological and immunohistochemical studies, a mucosa-associated lymphoid tissue (MALT) lymphoma was diagnosed. The patient underwent radiotherapy with no postoperative complications or recurrence. Early diagnosis and treatment of primary dural lymphoma is important. Histopathological evaluation is necessary for diagnosis. MRI cannot reliably differentiate between SDH and some dural lesions that present as diffuse infiltration. Therefore, these differential diagnoses should be considered.
颅内边缘区 B 细胞淋巴瘤表现为硬脑膜基底部肿块较为罕见。一位 45 岁女性，因全面性强直阵挛发作和言语障碍就诊于我院，病史 6 个月。影像学提示硬脑膜下血肿（SDH）。经保守随访，影像学表现或症状均无改善。因此，行开颅术以引流疑似 SDH。术中观察到硬脑膜斑块样增厚，未见 SDH，并进行了活检。经组织病理学和免疫组化研究，诊断为黏膜相关淋巴组织（MALT）淋巴瘤。患者行放疗，无术后并发症或复发。早期诊断和治疗原发性硬脑膜淋巴瘤非常重要。组织病理学评估对于诊断是必要的。MRI 不能可靠地区分 SDH 和某些表现为弥漫性浸润的硬脑膜病变。因此，应考虑这些鉴别诊断。
