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原发性硬脑膜淋巴瘤:8例患者治疗及预后的临床病理研究

Primary dural lymphomas: a clinicopathologic study of treatment and outcome in eight patients.

作者信息

Iwamoto Fabio M, DeAngelis Lisa M, Abrey Lauren E

机构信息

Department of Neurology and Neuroscience, Weill Medical College of Cornell University, New York, NY, USA.

出版信息

Neurology. 2006 Jun 13;66(11):1763-5. doi: 10.1212/01.wnl.0000218284.23872.eb.

Abstract

The authors report eight patients with primary dural lymphoma (PDL). All patients had extra-axial masses on MRI that diffusely enhanced after gadolinium. Pathology revealed low-grade non-Hodgkin lymphoma (marginal zone lymphoma of MALT [mucosa-associated lymphoid tissue] type) in all patients. All patients underwent radiation therapy, and three received chemotherapy. Complete response was achieved in 100% of patients, but three developed systemic relapse.

摘要

作者报告了8例原发性硬脑膜淋巴瘤(PDL)患者。所有患者在MRI上均有轴外肿块,注射钆后呈弥漫性强化。病理显示所有患者均为低级别非霍奇金淋巴瘤(黏膜相关淋巴组织边缘区淋巴瘤[MALT型])。所有患者均接受了放射治疗,3例接受了化疗。所有患者均实现完全缓解,但3例出现全身复发。

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