Cancer Institute, Imam Khomeini Hospital, Tehran University of Medical Sciences, Tehran, Iran.
Fertil Steril. 2010 Mar 1;93(4):1347.e17-8. doi: 10.1016/j.fertnstert.2009.09.065. Epub 2010 Jan 15.
To report a case of malignant transformation of abdominal wall endometriosis.
Case report.
Private practice.
PATIENT(S): A 59-year-old woman with a rapidly growing abdominal wall mass.
INTERVENTION(S): Neoadjuvant chemotherapy and surgical resection of the mass.
MAIN OUTCOME MEASURE(S): Shrinkage of the tumor after neoadjuvant chemotherapy and wide excision and reconstruction of abdominal wall.
RESULT(S): A 59-year-old woman had a history of laparotomy performed for uterine perforation due to dilatation and curettage 20 years ago. She noticed a mass in her abdominal wall shortly after the operation, which changed in size with menstrual cycles. The mass showed a rapid growth in the last 6 months before presentation. Incisional biopsy revealed papillary serous carcinoma. Owing to the large size of the mass, the patient received neoadjuvant chemotherapy and underwent surgery after shrinkage of the mass.
CONCLUSION(S): Malignant transformation of endometriosis is a rare event. In case of huge tumors, neoadjuvant chemotherapy might facilitate surgery by shrinking the tumor.
报告一例腹壁子宫内膜异位症恶变病例。
病例报告。
私人诊所。
一名 59 岁女性，腹壁肿块生长迅速。
新辅助化疗和肿块的广泛切除和重建。
新辅助化疗后肿瘤缩小，腹壁广泛切除和重建。
一名 59 岁女性因刮宫术致子宫穿孔 20 年前行剖腹术，术后不久即发现腹壁肿块，大小随月经周期变化。就诊前 6 个月肿块迅速生长。切开活检显示为乳头状浆液性癌。由于肿块巨大，患者接受了新辅助化疗，并在肿块缩小后进行了手术。
子宫内膜异位症恶变罕见。对于巨大肿瘤，新辅助化疗可能通过缩小肿瘤而有利于手术。
