Service d'Histologie-Embryologie-Cytogénétique-Biologie de la Reproduction-CECOS, Centre Hospitalier Universitaire Jean Verdier, Assistance Publique-Hôpitaux de Paris, Bondy, France.
Fertil Steril. 2010 Aug;94(3):1157-8. doi: 10.1016/j.fertnstert.2009.12.001. Epub 2010 Jan 15.
A retrospective analysis of a 5-year rescue intracytoplasmic sperm injection (ICSI) experience performed in 17 cases of complete IVF fertilization failure showed that the ongoing pregnancy rate per embryo transfer (ET) is much higher in a subsequent frozen-thawed cycles (40%, 2/5) than following a fresh ET (6.7%, 1/15). These results suggest that cryopreservation of all embryos, subsequently used in frozen-thawed cycles, might improve rescue ICSI outcome throughout a better synchronization of the embryo development with the endometrium.
回顾性分析了 17 例完全体外受精受精失败的患者 5 年的卵胞浆内单精子注射（ICSI）治疗经验，结果显示，在随后的冻融周期中每个胚胎移植（ET）的持续妊娠率（40%，2/5）明显高于新鲜 ET（6.7%，1/15）。这些结果表明，通过冷冻保存所有胚胎，随后在冻融周期中使用，可能通过更好地协调胚胎发育与子宫内膜同步来改善卵胞浆内单精子注射治疗的结局。
