葡萄糖对串珠镰刀菌产生 T-2 毒素的影响。
Glucose influence on the production of T-2 toxin by Fusarium sporotrichioides.
机构信息
Laboratory of Food Chemistry and Toxicology, Faculty of Pharmacy, University of València, València, Spain.
出版信息
Toxicon. 2010 Jun 1;55(6):1157-61. doi: 10.1016/j.toxicon.2010.01.005. Epub 2010 Jan 18.
Toxigenic isolate of Fusarium sporotrichioides was tested for the T-2 toxin production on PDA plates during 10 days under various glucose concentrations. T-2 toxin was determined by LC-MS and confirmed with LC-MS/MS. This analytical method has been applied, for the first time, to an extensive study of T-2 accumulation. Results showed that the production of this mycotoxin is directly correlated to the concentration of glucose present in the medium. Concentrations of T-2 toxin produced by the strain of F. sporotrichioides ranged from 0 to 1.45 mg/kg. The better T-2 production was evidenced in the fermentation operated with 20% of glucose.
产 T-2 毒素的串珠镰刀菌在不同葡萄糖浓度的 PDA 平板上经过 10 天的培养，检测其产毒情况。采用 LC-MS 并结合 LC-MS/MS 对 T-2 毒素进行了检测。该分析方法首次被应用于 T-2 毒素积累的广泛研究。结果表明，该真菌毒素的产生与培养基中葡萄糖的浓度直接相关。该串珠镰刀菌菌株产生的 T-2 毒素浓度范围为 0 至 1.45mg/kg。在发酵过程中使用 20%葡萄糖时，T-2 毒素的产量最高。
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