Laboratory of Organic Chemistry, Institute of Natural Products Chemistry, Vietnam Academy of Science and Technology, 18 Hoang Quoc Viet, Cau Giay, Hanoi, Viet Nam.
Fitoterapia. 2010 Sep;81(6):485-9. doi: 10.1016/j.fitote.2010.01.005. Epub 2010 Jan 15.
Phytochemical investigation of the methanol extract of Tinospora cordifolia aerial parts led to the isolation of four new and seven known compounds. The structures of two new aporphine alkaloids, N-formylasimilobine 2-O-beta-D-glucopyranosyl-(1-->2)-beta-D-glucopyranoside (tinoscorside A, 1) and N-acetylasimilobine 2-O-beta-D-glucopyranosyl-(1-->2)-beta-D-glucopyranoside (tinoscorside B, 2), a new clerodane diterpene, tinoscorside C (3), and a new phenylpropanoid, sinapyl 4-O-beta-D-apiofuranosyl-(1-->6)-O-beta-D-glucopyranoside (tinoscorside D, 6) were determined by extensive spectroscopic methods including FTICR-MS and 1D and 2D NMR.
从三叶鬼针草地上部分的甲醇提取物中分离得到了四个新化合物和七个已知化合物。两种新的阿朴菲生物碱，N-甲酰基阿朴啡碱 2-O-β-D-吡喃葡萄糖基-(1-->2)-β-D-吡喃葡萄糖苷（tinoscorside A，1）和 N-乙酰基阿朴啡碱 2-O-β-D-吡喃葡萄糖基-(1-->2)-β-D-吡喃葡萄糖苷（tinoscorside B，2），一个新的 clerodane 二萜，tinoscorside C（3），以及一个新的苯丙素，丁香酰基 4-O-β-D-阿魏酰基-(1-->6)-O-β-D-吡喃葡萄糖苷（tinoscorside D，6），通过广泛的光谱方法包括 FTICR-MS 和 1D 和 2D NMR 确定。
