Helbig D, Simon J C, Wetzig T, Paasch U
Klinik und Poliklinik für Dermatologie, Venerologie und Allergologie, Abt. Dermatohistologie, Universität Leipzig, Philipp Rosenthal Str. 23, 04103, Leipzig.
Hautarzt. 2010 Oct;61(10):885-7. doi: 10.1007/s00105-009-1899-6.
Desmoplastic fibroblastoma ("collagenous fibroma") is a rare benign, slowly progressive fibrous soft tissue tumor that ranges 1-20 cm in size. The tumor occurs in all ages, predominantly in the upper part of the body. Children are rarely affected. The tumor often infiltrates the subcutis; less often it invades the fascia and skeletal muscle or causes bone erosions. Histologically, the tumor is composed of spindle-shaped cells embedded in a densely collagenous stroma, sometimes forming a pseudo-capsule. Magnetic resonance imaging and computed tomography as well as ultrasonography are used to define the extensions of the tumor. Because it is clinically extremely difficult to determine if soft tissue tumors are benign or malignant, all should be excised with a margin of safety and examined histologically. We report a 22-year old woman with desmoplastic fibroblastoma located on the upper arm. Clinical and histopathological findings and treatment options are discussed.
促纤维组织增生性纤维瘤（“胶原纤维瘤”）是一种罕见的良性、缓慢进展的纤维性软组织肿瘤，大小在1至20厘米之间。该肿瘤可见于各年龄段，主要发生于身体上部。儿童很少受累。肿瘤常浸润皮下组织；较少侵犯筋膜和骨骼肌或引起骨质侵蚀。组织学上，肿瘤由嵌入致密胶原基质中的梭形细胞组成，有时形成假包膜。磁共振成像、计算机断层扫描以及超声检查用于确定肿瘤的范围。由于临床上极难判断软组织肿瘤是良性还是恶性，所有肿瘤均应在安全切缘下切除并进行组织学检查。我们报告一例22岁女性，其促纤维组织增生性纤维瘤位于上臂。讨论了临床和组织病理学发现及治疗选择。
