Department of Radiology Engineering University of California, Davis UC Davis Medical Center 4860 Y Street, ACC Suite 3100 Sacramento, CA 95817, USA.
Technol Cancer Res Treat. 2010 Feb;9(1):29-44. doi: 10.1177/153303461000900104.
Mammography has served the population of women who are at-risk for breast cancer well over the past 30 years. While mammography has undergone a number of changes as digital detector technology has advanced, other modalities such as computed tomography have experienced technological sophistication over this same time frame as well. The advent of large field of view flat panel detector systems enable the development of breast CT and several other niche CT applications, which rely on cone beam geometry. The breast, it turns out, is well suited to cone beam CT imaging because the lack of bones reduces artifacts, and the natural tapering of the breast anteriorly reduces the x-ray path lengths through the breast at large cone angle, reducing cone beam artifacts as well. We are in the process of designing a third prototype system which will enable the use of breast CT for image guided interventional procedures. This system will have several copies fabricated so that several breast CT scanners can be used in a multi-institutional clinical trial to better understand the role that this technology can bring to breast imaging.
乳腺 X 线摄影在过去的 30 多年里为乳腺癌高危人群服务得很好。虽然随着数字探测器技术的进步,乳腺 X 线摄影已经经历了许多变化,但在同一时期,其他模态,如计算机断层扫描(CT),也经历了技术的复杂性。大视野平板探测器系统的出现使得乳腺 CT 和其他一些依赖锥形束几何结构的特定 CT 应用的发展成为可能。事实证明,乳腺非常适合锥形束 CT 成像,因为缺乏骨骼可以减少伪影,而且乳腺前部的自然变细可以减少大角度锥形束通过乳腺的射线路径长度,从而减少锥形束伪影。我们正在设计第三个原型系统,该系统将能够使用乳腺 CT 进行图像引导介入手术。该系统将制造多个副本,以便在多机构临床试验中使用多个乳腺 CT 扫描仪,以更好地了解该技术在乳腺成像中的作用。