Department of Dermatology, the Methodist Hospital, Houston, Texas; DermSurgery Associates, Houston, Texas.
Department of Dermatology, the Methodist Hospital, Houston, Texas; DermSurgery Associates, Houston, Texas.
J Am Acad Dermatol. 2010 Jan;62(1):102-106. doi: 10.1016/j.jaad.2009.06.066.
Desmoplastic trichoepithelioma (DTE) is an uncommon adnexal tumor usually found on the face of young women.
We sought to describe the clinical and histologic characteristics of DTE and discuss management strategies for these tumors.
We conducted a retrospective case series and review of the literature.
A series of 17 cases of DTE is reported. Of our patients, 82% were female and half of all these cases occurred on the cheek. Unlike previous reports, the patients in our study were slightly older, with 53% older than 51 years and 71% between the ages of 31 and 60 years at the time of surgery (mean age 49 years, median age 52 years, range 14-81 years). Approximately 38% of the tumors had been present for 1 to 2 years before presentation. The average size of the tumors at the time of surgery was 0.8 x 0.6 cm. All cases were treated with Mohs micrographic surgery. To date, none of the tumors have recurred.
This is a small case series. The referral patterns of our predominantly Mohs micrographic surgery clinic might further bias this study.
DTE is a benign tumor that has a predilection for the face. With its rapid growth, aggressive histologic features that may be confused with basal cell carcinoma, and tendency to arise in cosmetically and functionally sensitive areas, these tumors should be removed in a manner that assures clear surgical margins, such as Mohs micrographic surgery.
促结缔组织增生性毛上皮瘤（DTE）是一种罕见的附属器肿瘤，通常发生在年轻女性的面部。
我们旨在描述 DTE 的临床和组织学特征，并讨论这些肿瘤的治疗策略。
我们进行了回顾性病例系列研究和文献复习。
报告了一系列 17 例 DTE 患者。我们的患者中 82%为女性，其中一半的病例发生在脸颊。与以往的报告不同，我们研究中的患者年龄稍大，53%的患者年龄大于 51 岁，71%的患者在手术时年龄在 31 至 60 岁之间（平均年龄 49 岁，中位年龄 52 岁，范围 14-81 岁）。大约 38%的肿瘤在就诊前已存在 1 至 2 年。手术时肿瘤的平均大小为 0.8 x 0.6 厘米。所有病例均采用 Mohs 显微外科手术治疗。迄今为止，没有肿瘤复发。
这是一个小的病例系列。我们的 Mohs 显微外科手术诊所的转诊模式可能会进一步影响本研究。
DTE 是一种良性肿瘤，好发于面部。由于其生长迅速、组织学特征具有侵袭性，可能与基底细胞癌混淆，且倾向于发生在美容和功能敏感区域，因此这些肿瘤应通过确保明确的手术切缘的方式切除，如 Mohs 显微外科手术。
