Department of Dermatology, Hospital Universitari Germans Trias i Pujol, Carretera de Canyet s/n, 08916-Badalona, Spain.
Clin Dermatol. 2010 Jan-Feb;28(1):81-7. doi: 10.1016/j.clindermatol.2009.03.002.
During the last 30 years, the tremendous progress in our knowledge of the pathogenesis of psoriasis has led to the development of new agents, the so-called biologics, that have revolutionized the management of severe psoriasis. Dermatologists and patients see this emerging therapy as a new perspective in the state of the art in managing moderate to severe psoriasis. After a few years of use in daily practice, we may begin to analyze the power of the currently available biologic agents in the management of severe psoriasis from the perspective of facts.
在过去的 30 年中，我们对银屑病发病机制的认识取得了巨大的进展，这导致了新的治疗药物的发展，即所谓的生物制剂，它们彻底改变了严重银屑病的治疗方法。皮肤科医生和患者认为这种新兴疗法为中重度银屑病的治疗提供了新视角。在日常实践中使用了几年之后，我们也许可以从实际情况的角度开始分析目前可用的生物制剂在严重银屑病治疗中的作用。
