• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

氧化应激与认知长寿。

Oxidative stress and cognitive longevity.

机构信息

The Nutrition Doctor, Skokie, Illinois, USA.

出版信息

Nutrition. 2010 Jun;26(6):595-603. doi: 10.1016/j.nut.2009.09.014. Epub 2010 Jan 18.

DOI:10.1016/j.nut.2009.09.014
PMID:20083385
Abstract

OBJECTIVE

The potential relation between metabolic activity within the central nervous system and retention of cognitive functioning capacity was assessed.

METHODS

A detailed literature review was conducted and summarized.

RESULTS

A large body of scientific evidence describes the interactions among cognitive activity, oxidative stress, neurodegeneration, neuroprotection, cognitive aging, and retention of cognitive functioning ability.

CONCLUSION

Maintenance of redox balance within the central nervous system can forestall cognitive decline and promote cognitive longevity.

摘要

目的

评估中枢神经系统代谢活性与认知功能保留能力之间的潜在关系。

方法

进行了详细的文献回顾并加以总结。

结果

大量科学证据描述了认知活动、氧化应激、神经退行性变、神经保护、认知老化和认知功能保留能力之间的相互作用。

结论

维持中枢神经系统内的氧化还原平衡可以防止认知能力下降，促进认知长寿。

相似文献

1
Oxidative stress and cognitive longevity.氧化应激与认知长寿。
Nutrition. 2010 Jun;26(6):595-603. doi: 10.1016/j.nut.2009.09.014. Epub 2010 Jan 18.
2
Dietary supplementation with apple juice concentrate alleviates the compensatory increase in glutathione synthase transcription and activity that accompanies dietary- and genetically-induced oxidative stress.补充浓缩苹果汁饮食可缓解因饮食和基因诱导的氧化应激所伴随的谷胱甘肽合成酶转录和活性的代偿性增加。
J Nutr Health Aging. 2004;8(6):492-6.
3
Apple juice prevents oxidative stress and impaired cognitive performance caused by genetic and dietary deficiencies in mice.苹果汁可预防小鼠因基因和饮食缺陷引起的氧化应激及认知能力受损。
J Nutr Health Aging. 2004;8(2):92-7.
4
Phosphatidylserine and the human brain.磷脂酰丝氨酸与人类大脑。
Nutrition. 2015 Jun;31(6):781-6. doi: 10.1016/j.nut.2014.10.014. Epub 2014 Nov 4.
5
Oxidative stress and cognitive impairment in the elderly.老年人的氧化应激与认知障碍
J Nutr Health Aging. 2002;6(4):261-6.
6
Mitochondrial dysfunction and oxidative stress in neurodegenerative diseases.神经退行性疾病中的线粒体功能障碍与氧化应激
Nature. 2006 Oct 19;443(7113):787-95. doi: 10.1038/nature05292.
7
Vitamin E and other endogenous antioxidants in the central nervous system.中枢神经系统中的维生素E及其他内源性抗氧化剂。
Geriatrics. 1998 Sep;53 Suppl 1:S25-7.
8
Mitochondria, metabolic disturbances, oxidative stress and the kynurenine system, with focus on neurodegenerative disorders.线粒体、代谢紊乱、氧化应激与犬尿氨酸系统，重点关注神经退行性疾病
J Neurol Sci. 2007 Jun 15;257(1-2):221-39. doi: 10.1016/j.jns.2007.01.033. Epub 2007 Apr 25.
9
Dietary supplementation with a combination of alpha-lipoic acid, acetyl-L-carnitine, glycerophosphocoline, docosahexaenoic acid, and phosphatidylserine reduces oxidative damage to murine brain and improves cognitive performance.补充包含α-硫辛酸、乙酰左旋肉碱、甘油磷酸胆碱、二十二碳六烯酸和磷脂酰丝氨酸的组合膳食可减少对小鼠大脑的氧化损伤并改善认知能力。
Nutr Res. 2009 Jan;29(1):70-4. doi: 10.1016/j.nutres.2008.11.004.
10
Cognitive reserve and the neurobiology of cognitive aging.认知储备与认知衰老的神经生物学
Ageing Res Rev. 2004 Nov;3(4):369-82. doi: 10.1016/j.arr.2004.05.001.

引用本文的文献

1
The relationship between hand grip strength and cognitive function in middle-aged and elderly people in China: A cross-sectional analysis based on CHARLS data.中国中老年人握力与认知功能的关系：基于中国健康与养老追踪调查（CHARLS）数据的横断面分析
Medicine (Baltimore). 2025 Jul 25;104(30):e43587. doi: 10.1097/MD.0000000000043587.
2
Molecular Mechanisms, Endurance Athlete, and Synergistic Therapeutic Effects of Marine-Derived Antioxidant Astaxanthin Supplementation and Exercise in Cancer, Metabolic Diseases, and Healthy Individuals.海洋来源的抗氧化剂虾青素补充剂与运动在癌症、代谢性疾病及健康个体中的分子机制、耐力运动员及协同治疗作用
Food Sci Nutr. 2025 Jun 27;13(7):e70470. doi: 10.1002/fsn3.70470. eCollection 2025 Jul.
3
The Effects of Astaxanthin on Cognitive Function and Neurodegeneration in Humans: A Critical Review.
虾青素对人类认知功能和神经退行性变的影响：一项批判性综述。
Nutrients. 2024 Mar 14;16(6):826. doi: 10.3390/nu16060826.
4
A Narrative Review: The Effect and Importance of Carotenoids on Aging and Aging-Related Diseases.综述：类胡萝卜素对衰老和衰老相关疾病的影响和重要性。
Int J Mol Sci. 2023 Oct 15;24(20):15199. doi: 10.3390/ijms242015199.
5
The effects of typical ageing on cognitive control: recent advances and future directions.典型衰老对认知控制的影响：最新进展与未来方向。
Front Aging Neurosci. 2023 Jul 28;15:1231410. doi: 10.3389/fnagi.2023.1231410. eCollection 2023.
6
Cognitive Functions in Obsessive Compulsive Disorder and Its Relationship with Oxidative Metabolism.强迫症中的认知功能及其与氧化代谢的关系。
Noro Psikiyatr Ars. 2023 Apr 28;60(2):134-142. doi: 10.29399/npa.28122. eCollection 2023.
7
NMN Alleviates NP-Induced Learning and Memory Impairment Through SIRT1 Pathway in PC-12 Cell.烟酰胺单核苷酸通过SIRT1通路减轻PC-12细胞中神经肽诱导的学习和记忆损伤。
Mol Neurobiol. 2023 May;60(5):2871-2883. doi: 10.1007/s12035-023-03251-9. Epub 2023 Feb 6.
8
Selenomethionine Ameliorates Cognitive Impairment, Decreases Hippocampal Oxidative Stress and Attenuates Dysbiosis in D-Galactose-Treated Mice.硒代蛋氨酸改善D-半乳糖处理小鼠的认知障碍，降低海马氧化应激并减轻肠道菌群失调。
Antioxidants (Basel). 2022 Jan 4;11(1):111. doi: 10.3390/antiox11010111.
9
Molecular markers of DNA repair and brain metabolism correlate with cognition in centenarians.端粒长度、DNA 修复和脑代谢的分子标志物与百岁老人的认知功能相关。
Geroscience. 2022 Feb;44(1):103-125. doi: 10.1007/s11357-021-00502-2. Epub 2021 Dec 29.
10
100% Watermelon Juice as a Food-First Intervention to Improve Cognitive Function: Ancillary Findings from a Randomized Controlled Trial.100% 西瓜汁作为改善认知功能的饮食干预手段：一项随机对照试验的辅助发现。
J Nutr Gerontol Geriatr. 2021 Oct-Dec;40(4):304-312. doi: 10.1080/21551197.2021.1988028. Epub 2021 Oct 13.