Department of Communication Sciences, Northwestern University, Evanston, Illinois 60208, USA.
Ear Hear. 2010 Jun;31(3):302-24. doi: 10.1097/AUD.0b013e3181cdb272.
This tutorial provides a comprehensive overview of the methodological approach to collecting and analyzing auditory brain stem responses to complex sounds (cABRs). cABRs provide a window into how behaviorally relevant sounds such as speech and music are processed in the brain. Because temporal and spectral characteristics of sounds are preserved in this subcortical response, cABRs can be used to assess specific impairments and enhancements in auditory processing. Notably, subcortical auditory function is neither passive nor hardwired but dynamically interacts with higher-level cognitive processes to refine how sounds are transcribed into neural code. This experience-dependent plasticity, which can occur on a number of time scales (e.g., life-long experience with speech or music, short-term auditory training, on-line auditory processing), helps shape sensory perception. Thus, by being an objective and noninvasive means for examining cognitive function and experience-dependent processes in sensory activity, cABRs have considerable utility in the study of populations where auditory function is of interest (e.g., auditory experts such as musicians, and persons with hearing loss, auditory processing, and language disorders). This tutorial is intended for clinicians and researchers seeking to integrate cABRs into their clinical or research programs.
本教程全面介绍了采集和分析复杂声音的听觉脑干反应(cABR)的方法学方法。cABR 为我们提供了一个窗口,可以了解言语和音乐等与行为相关的声音在大脑中的处理方式。由于声音的时间和频谱特征在这种皮质下反应中得以保留,因此 cABR 可用于评估听觉处理的特定损伤和增强。值得注意的是,皮质下听觉功能既不是被动的,也不是固定不变的,而是与高级认知过程动态相互作用,以完善声音如何转化为神经编码。这种依赖经验的可塑性可以在多个时间尺度上发生(例如,终生接触言语或音乐、短期听觉训练、在线听觉处理),有助于塑造感觉知觉。因此,cABR 作为一种客观、非侵入性的方法,可以用于检查认知功能和感觉活动中的经验依赖性过程,因此在研究听觉功能感兴趣的人群(例如听觉专家如音乐家,以及有听力损失、听觉处理和语言障碍的人群)中具有相当大的效用。本教程面向希望将 cABR 整合到其临床或研究计划中的临床医生和研究人员。