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1
Incidence of cerebrospinal fluid leak following petrosectomy and analysis of avoidance techniques.经岩骨乙状窦后入路切除术后脑脊液漏的发生率及预防技术分析。
J Clin Neurosci. 2012 Jan;19(1):92-4. doi: 10.1016/j.jocn.2011.08.001. Epub 2011 Nov 21.
2
Management of cerebrospinal fluid leaks after vestibular schwannoma surgery.前庭神经鞘瘤手术后脑脊液漏的处理。
Otol Neurotol. 2011 Dec;32(9):1525-9. doi: 10.1097/MAO.0b013e318232e4a4.
3
Prevention of cerebrospinal fluid leak after translabyrinthine resection of vestibular schwannoma.预防经迷路切除前庭神经鞘瘤后脑脊液漏
Otol Neurotol. 2010 Apr;31(3):473-7. doi: 10.1097/MAO.0b013e3181cdd8fc.
4
Safety and efficacy of the porcine small intestinal submucosa dural substitute: results of a prospective multicenter study and literature review.猪小肠黏膜下层硬脑膜替代物的安全性和有效性:一项前瞻性多中心研究结果及文献综述
J Neurosurg. 2007 Jun;106(6):1028-33. doi: 10.3171/jns.2007.106.6.1028.
5
Comparison of different wound closure techniques in translabyrinthine acoustic neuroma surgery.经迷路入路听神经瘤手术中不同伤口闭合技术的比较
Skull Base Surg. 1999;9(4):239-42. doi: 10.1055/s-2008-1058132.
6
The incidence of cerebrospinal fluid leak after vestibular schwannoma surgery.前庭神经鞘瘤手术后脑脊液漏的发生率。
Otol Neurotol. 2004 May;25(3):387-93. doi: 10.1097/00129492-200405000-00030.
7
Cerebrospinal fluid leak after acoustic neuroma surgery: a comparison of the translabyrinthine, middle fossa, and retrosigmoid approaches.听神经瘤手术后脑脊液漏:经迷路、中颅窝和乙状窦后入路的比较
Otol Neurotol. 2003 Jan;24(1):107-12. doi: 10.1097/00129492-200301000-00021.
8
No cerebrospinal fluid leaks in translabyrinthine vestibular schwannoma removal: reappraisal of 200 consecutive patients.经迷路入路切除前庭神经鞘瘤术中无脑脊液漏:对200例连续患者的重新评估
Am J Otol. 1999 Sep;20(5):660-6.
9
Wound closure after acoustic neuroma surgery.听神经瘤手术后的伤口闭合
Br J Neurosurg. 1993;7(2):171-4. doi: 10.3109/02688699309103474.

经迷路入路听神经瘤手术中的硬脑膜缺损修复及其与脑脊液漏发生的关系

Dural defect repair in translabyrinthine acoustic neuroma surgery and its implications in cerebrospinal fluid leak occurrence.

作者信息

Netto Aloysio Augusto Tahan de Campos, Colafêmina José Fernando, Centeno Ricardo Silva

机构信息

Department of Otolaryngology-Head and Neck Surgery, Scholl of Medicine of Ribeirão Preto, University of São Paulo, Ribeirão Preto-SP, Brazil.

出版信息

J Neurol Surg B Skull Base. 2012 Oct;73(5):327-30. doi: 10.1055/s-0032-1321511.

DOI:10.1055/s-0032-1321511
PMID:24083124
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3578640/
Abstract

Cerebrospinal fluid (CSF) leak is a complication that may occur after translabyrinthine (translab) acoustic neuroma (AN) removal. The aim of this study is to verify the incidence of CSF leak using two techniques for dural defect closure in translab AN surgery and present a new technique for dural repair. A retrospective study was held, reviewing charts of 34 patients in a tertiary neurotologic referral center. Out of these 34 patients that underwent translab AN excision in a 1-year period, 18 had their dural defect repaired using only abdominal fat graft and 16 using synthetic dura substitute (SDS) plus abdominal fat tissue. One patient (5.5%) in the first group had CSF leak and 1 (6.2%) in the second group had CSF leak postoperatively. Our data suggest that there are no significant differences in CSF leak rates using both techniques, although studies in a larger series must be undertaken to conclude it. We believe that the development of some points in the new technique for dural repair can achieve better results and reduce the CSF leak incidence in the translabyrinthine acoustic neuroma surgery in the near future.

摘要

脑脊液漏是经迷路入路切除听神经瘤后可能出现的一种并发症。本研究旨在验证经迷路入路听神经瘤手术中两种硬脑膜缺损闭合技术导致脑脊液漏的发生率,并提出一种新的硬脑膜修复技术。我们进行了一项回顾性研究,查阅了一家三级神经耳科转诊中心34例患者的病历。在这34例于1年内接受经迷路入路听神经瘤切除术的患者中,18例仅使用腹部脂肪移植修复硬脑膜缺损,16例使用人工硬脑膜替代物(SDS)加腹部脂肪组织进行修复。第一组中有1例患者(5.5%)术后发生脑脊液漏,第二组中有1例患者(6.2%)术后发生脑脊液漏。我们的数据表明,尽管必须进行更大样本量的研究才能得出结论,但两种技术导致脑脊液漏的发生率并无显著差异。我们相信,新的硬脑膜修复技术中某些要点的改进在不久的将来能够取得更好的效果,并降低经迷路入路听神经瘤手术中脑脊液漏的发生率。