Chad Z
Chair, Canadian Allergy, Asthma and Immunology Foundation, Ottawa, Ontario.
Paediatr Child Health. 2001 Oct;6(8):555-66. doi: 10.1093/pch/6.8.555.
Allergic diseases in children have increased significantly in recent years and now affect up to 35% of children. They are a major cause of morbidity in children. Although there is a genetic predisposition, it is the exposure to environmental allergens, irritants and infections that will determine the sensitization to different dietary and inhalant allergens. As the genetic and environmental factors that act on an immature cellular immune system are better elucidated and their roles established, the implementation of more enduring preventive efforts will be developed. However, at present, the best approach to the child at high risk for the development of allergies is to institute dietary and environmental control measures early to decrease sensitization, and to recognize and appropriately treat the evolving signs and symptoms of allergic disease.
近年来,儿童过敏性疾病显著增加,目前影响着高达35%的儿童。它们是儿童发病的主要原因。虽然存在遗传易感性,但正是接触环境过敏原、刺激物和感染因素决定了对不同饮食和吸入性过敏原的致敏情况。随着作用于未成熟细胞免疫系统的遗传和环境因素得到更好的阐释及其作用得以明确,将制定更持久的预防措施。然而,目前对于有过敏发展高风险的儿童,最佳方法是尽早采取饮食和环境控制措施以减少致敏,并识别和适当治疗过敏性疾病不断演变的体征和症状。