Furberg C D
Department of Public Health Sciences, Bowman Gray School of Medicine, Winston-Salem, North Carolina 27103.
Prev Med. 1991 Jan;20(1):158-61. doi: 10.1016/0091-7435(91)90016-w.
Careful and thorough planning are essential aspects of a clinical trial that can make the difference and lead to a more successful trial. The value of feasibility studies should be recognized. The use of surrogate endpoints has justifiably come under increased scrutiny. The many complex issues of implementation demand experienced trial investigators. An openness to learn from lessons in previous trials is essential.
精心且全面的规划是临床试验的关键要素，它能产生影响并促成更成功的试验。应认识到可行性研究的价值。替代终点的使用理所当然受到了更多审视。诸多复杂的实施问题需要经验丰富的试验研究者。乐于从前瞻性试验中吸取经验教训至关重要。
