Key Laboratory of Functional Polymer Materials, Ministry of Education, Department of Chemistry, Nankai University, Tianjin 300071, People's Republic of China.
Langmuir. 2010 Jun 1;26(11):8762-8. doi: 10.1021/la904519j.
Colloidal particles with polystyrene (PS) cores and gold nanoparticle (AuNP) coronae were prepared on the basis of the self-assembly of AuNP's and PS. Citrate-stabilized AuNP's were dispersed in aqueous solution, and PS with thiol terminal groups (PS-SH) was dissolved in toluene. A stable emulsion was obtained by mixing the two solutions. Optical microscope images indicate that after grafting of PS-SH to the citrate-stabilized AuNP's at liquid-liquid interface, the interfacial tension is reduced and the average size of toluene droplets in the emulsion decreases. Transmission electron microscope (TEM) results also prove the grafting of PS-SH to AuNP's and the location of the hybrid nanoparticles at the liquid-liquid interface. Colloidal particles with PS cores and AuNP coronae were prepared by adding the emulsion to excess methanol. The weight ratio of PS-SH to AuNP exerts a significant effect on the size of colloidal particles. TEM and dynamic light scattering results both indicate that the size of colloidal particles increases with the weight ratio. The application of the core-shell-structured colloidal particles to protein separation was also investigated in this research. Colloidal particles with PS-coated magnetic nanoparticles in the cores were also prepared by this strategy.
基于金纳米粒子（AuNP）和聚苯乙烯（PS）的自组装，制备了具有 PS 核和 AuNP 冠的胶体粒子。将柠檬酸钠稳定的 AuNP 分散在水溶液中，将带有巯基末端基团的 PS（PS-SH）溶解在甲苯中。通过混合两种溶液得到稳定的乳液。光学显微镜图像表明，在液-液界面上将 PS-SH 接枝到柠檬酸钠稳定的 AuNP 上后，界面张力降低，乳液中甲苯液滴的平均尺寸减小。透射电子显微镜（TEM）结果也证明了 PS-SH 接枝到 AuNP 上以及杂化纳米粒子在液-液界面上的位置。通过将乳液加入过量甲醇中制备具有 PS 核和 AuNP 冠的胶体粒子。PS-SH 与 AuNP 的重量比对胶体粒子的尺寸有显著影响。TEM 和动态光散射结果均表明，胶体粒子的尺寸随重量比的增加而增大。本研究还考察了核壳结构胶体粒子在蛋白质分离中的应用。还通过该策略制备了具有 PS 包覆的磁性纳米粒子核的胶体粒子。
