Department of Chemistry, BK21 Program, Polymer Research Institute, Pohang University of Science and Technology (POSTECH), Pohang 790-784, Korea.
Chem Commun (Camb). 2010 Feb 7;46(5):692-4. doi: 10.1039/b920753h. Epub 2009 Dec 16.
The work demonstrates a judicious approach to achieve hepatocyte cell-targeted highly efficient gene delivery by utilizing a supramolecular complex of galactosylated cucurbituril and dextran-spermine conjugates.
该工作展示了一种明智的方法,通过利用半乳糖化葫芦[7]脲和葡聚糖-精胺缀合物的超分子复合物,实现了对肝细胞的高效靶向基因传递。