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[全科医疗中儿童化脓性脑膜炎的诊断问题]

[Diagnostic problems of purulent meningitis in children in general practice].

作者信息

Hansen H, Sørensen H T

机构信息

Børneafdelingen, Aalborg Sygehus.

出版信息

Ugeskr Laeger. 1991 Feb 25;153(9):654-7.

PMID:2008759
Abstract

Previous investigations have demonstrated that considerable problems may exist in the diagnosis of purulent meningitis (PM) in general practice. Referrals from general practitioners/duty roster doctors concerning 97 children discharged the diagnosis of PM were reviewed retrospectively. The patients were subdivided into two groups according to whether the diagnosis was established by the referring doctor or not. Only 35% of the children under one year were admitted for suspected PM, whereas 65% of the children between one year and 15 year were hospitalized with the correct diagnosis. The commonest positive findings in both age groups were alterations in consciousness which were found in more than 80% of the children. Children in whom the diagnosis was not established by the referring doctor had fewer classical signs of meningitis (neck-stiffness, Kernig's sign, bulging fontanelle and petecchia) than children in whom the diagnosis was established. Children with negative cultures from the cerebro-spinal fluid were significantly more frequently treated with antibiotics prior to hospitalization. Approximately half of the children admitted with suspected meningitis were not treated according the guidelines issued by the Danish Board of Health, without this having any effect on the survival rate.

摘要

以往的调查表明,在全科医疗中,化脓性脑膜炎(PM)的诊断可能存在相当大的问题。对全科医生/值班名册医生转诊的97例确诊为PM的出院儿童进行了回顾性研究。根据转诊医生是否确诊,将患者分为两组。一岁以下儿童中只有35%因疑似PM入院,而一岁至15岁儿童中有65%因正确诊断而住院。两个年龄组最常见的阳性体征是意识改变,超过80%的儿童出现这种情况。转诊医生未确诊的儿童比确诊的儿童有更少的脑膜炎典型体征(颈部僵硬、克氏征、囟门隆起和瘀点)。脑脊液培养阴性的儿童在住院前接受抗生素治疗的频率明显更高。约一半因疑似脑膜炎入院的儿童未按照丹麦卫生局发布的指南进行治疗,但这对生存率没有任何影响。

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