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基于电化学电池的传感器。

Electrochemical cell-based sensors.

机构信息

Department of Molecular Microbiology and Biotechnology, Faculty of Life Sciences, Tel-Aviv University, Tel-Aviv, 69978, Israel,

出版信息

Adv Biochem Eng Biotechnol. 2010;117:77-84. doi: 10.1007/10_2009_17.

Abstract

One of the recently developed monitoring technologies involves the use of whole cell biosensors. Such biosensors can be constructed to detect expression of genes of interest and the effect of the environment on this expression. These biosensors are essential for monitoring environmental stress, such as general toxicity or specific toxicity caused by pollutants. Currently, a large spectrum of microbial biosensors have been developed that enable the monitoring of gene expression by measuring light, fluorescence, color, or electric current. The electrochemical monitoring is of special interest for in situ measurements as it can be performed using simple, compact, and mobile equipment and is easily adaptable for online measurements. Here we survey the potential application of electrochemical biosensors with special focus on monitoring environmental pollution.

摘要

最近开发的监测技术之一涉及全细胞生物传感器的使用。此类生物传感器可用于检测感兴趣基因的表达以及环境对该表达的影响。这些生物传感器对于监测环境压力(例如由污染物引起的一般毒性或特定毒性)至关重要。目前,已经开发出了大量的微生物生物传感器,这些传感器可以通过测量光、荧光、颜色或电流来监测基因表达。电化学监测特别适用于原位测量,因为它可以使用简单、紧凑和移动的设备进行,并且易于适应在线测量。在这里,我们调查了电化学生物传感器的潜在应用,特别关注监测环境污染。

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