Department of Environmental Chemistry, Institute of Environmental Assessment and Water Research (IDAEA-CSIC), Jordi Girona 18, 08034 Barcelona, Catalonia, Spain.
Ecotoxicol Environ Saf. 2010 May;73(4):559-64. doi: 10.1016/j.ecoenv.2009.12.030. Epub 2010 Jan 20.
Sediment quality guidelines and toxic equivalent factors have been used for assessment of the toxicity of sedimentary long-range atmospherically transported polycyclic aromatic hydrocarbons (PAHs) to the organisms living in high mountain European lakes. This method has provided indices that are consistent with experimental studies evaluating in situ sedimentary estrogenic activity or physiological response to AhR binding in fish from the same lakes. All examined lakes in north, central, west, northeast and southeast European mountains have shown sedimentary PAH concentrations that are above thresholds of no effect but only those situated in the southeast lakes district exhibited concentrations above the indices of probable effects. These mountains, Tatras, are also those having PAH concentrations of highest activity for AhR binding. Chrysene+triphenylene, dibenz[a]anthracene, benzo[k]fluoranthene and indeno[1,2,3-cd]pyrene are the main compounds responsible for the observed toxic effects.
已使用沉积物质量准则和毒性等效系数来评估高山欧洲湖泊中生活的生物体所受长距离大气传输多环芳烃 (PAH) 沉积物毒性。该方法提供的指数与评估同一湖泊鱼类原位沉积物雌激素活性或 AhR 结合生理反应的实验研究一致。对来自北欧、中欧、西欧、东北欧和东南欧山区的所有受检湖泊的研究均表明，其沉积物 PAH 浓度均高于无显著影响阈值，但只有东南湖区的湖泊显示出浓度高于可能产生影响的指数。这些山区（塔特拉山脉）的 PAH 浓度也具有最高的 AhR 结合活性。䓛+三联苯、二苯并[a,h]蒽、苯并[k]荧蒽和茚并[1,2,3-cd]芘是造成观察到的毒性影响的主要化合物。
