Hickey R, Hoffman J, Ramamurthy S
Department of Anesthesiology, University of Texas Health Science Center, San Antonio 78284.
Anesthesiology. 1991 Apr;74(4):639-42. doi: 10.1097/00000542-199104000-00002.
This study compared the effectiveness of 0.5% ropivacaine and 0.5% bupivacaine for brachial plexus block. Forty-eight patients received a subclavian perivascular brachial plexus block for upper-extremity surgery. One group (n = 24) received ropivacaine 0.5% (175 mg) and a second group (n = 24) received bupivacaine 0.5% (175 mg), both without epinephrine. Onset times for analgesia and anesthesia in each of the C5 through T1 brachial plexus dermatomes did not differ significantly between groups. Duration of analgesia and anesthesia was long (mean duration of analgesia, 13-14 h; mean duration of anesthesia, 9-11 h) and also did not differ significantly between groups. Motor block was profound, with shoulder paralysis as well as hand paresis developing in all of the patients in both groups. Two patients in each group required supplemental blocks before surgery. Ropivacaine 0.5% and bupivacaine 0.5% appeared equally effective in providing brachial plexus anesthesia.
本研究比较了0.5%罗哌卡因和0.5%布比卡因用于臂丛神经阻滞的效果。48例患者接受锁骨下血管周围臂丛神经阻滞以进行上肢手术。一组（n = 24）接受0.5%罗哌卡因（175 mg），另一组（n = 24）接受0.5%布比卡因（175 mg），两组均未加肾上腺素。在C5至T1臂丛神经皮节中，两组间镇痛和麻醉的起效时间无显著差异。镇痛和麻醉的持续时间较长（平均镇痛持续时间为13 - 14小时；平均麻醉持续时间为9 - 11小时），两组间也无显著差异。运动阻滞较深，两组所有患者均出现肩部麻痹和手部无力。每组各有2例患者在手术前需要追加阻滞。0.5%罗哌卡因和0.5%布比卡因在提供臂丛神经麻醉方面似乎同样有效。
