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在荷兰初级保健中通过生活方式干预识别适合 2 型糖尿病预防的个体的积极策略:APHRODITE 研究。

An active strategy to identify individuals eligible for type 2 diabetes prevention by lifestyle intervention in Dutch primary care: the APHRODITE study.

机构信息

Scientific Centre for Transformation in Care and Welfare (Tranzo), University of Tilburg, Tilburg.

出版信息

Fam Pract. 2010 Jun;27(3):312-9. doi: 10.1093/fampra/cmp100. Epub 2010 Jan 20.

Abstract

BACKGROUND

Several trials have shown the potential of lifestyle intervention programmes for prevention of type 2 diabetes. The effectiveness of implementation of these programmes into daily practice is now being studied in several countries. The 'Active Prevention in High Risk individuals of Diabetes Type 2 in Eindhoven' (APHRODITE) study investigates whether type 2 diabetes prevention by lifestyle intervention is effective in Dutch primary care. In this article we describe the process of recruiting the study participants.

OBJECTIVE

To assess the reach of an active strategy to recruit participants for a programme on type 2 diabetes prevention by lifestyle intervention in Dutch primary care.

METHODS

A diabetes risk questionnaire was sent to general practice patients aged 40-70 years. Individuals with a risk score above threshold were invited for an admission interview with the GP and an oral glucose tolerance test (OGTT). All individuals with non-diabetic glucose levels were asked to participate in the intervention study.

RESULTS

In total, 8752 (54.6%) of the individuals returned the questionnaire in time. Of all high-risk individuals (n = 1533), 73.1% contacted their practice to schedule a consultation with the GP. Response rates varied significantly among practices.

CONCLUSIONS

Using invitational letters, a substantial amount of individuals could be motivated to participate in a programme on type 2 diabetes prevention by lifestyle intervention in Dutch primary care. Further research is needed on what kind of strategy would be most effective and efficient to screen for individuals at high risk for type 2 diabetes in primary care.

摘要

背景

多项试验表明,生活方式干预方案在预防 2 型糖尿病方面具有潜力。目前,多个国家正在研究将这些方案实际应用于日常实践的效果。“艾恩德霍芬高危 2 型糖尿病主动预防(APHRODITE)”研究旨在评估荷兰初级保健中通过生活方式干预预防 2 型糖尿病的效果。本文介绍了研究参与者的招募流程。

目的

评估在荷兰初级保健中通过生活方式干预预防 2 型糖尿病的方案采用主动策略招募参与者的效果。

方法

向年龄在 40-70 岁之间的全科医学患者发送糖尿病风险问卷。得分高于阈值的个体将被邀请与全科医生进行入院访谈,并进行口服葡萄糖耐量试验(OGTT)。所有血糖水平正常的个体都被要求参加干预研究。

结果

共有 8752 人(54.6%)及时返回问卷。所有高风险个体(n=1533)中,73.1%联系其诊所安排与全科医生的咨询。各诊所的回复率差异显著。

结论

通过邀请函,可在很大程度上激励荷兰初级保健中大量个体参与到生活方式干预的 2 型糖尿病预防方案中。需要进一步研究在初级保健中筛查 2 型糖尿病高危个体时哪种策略最有效和高效。

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