• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

仅在产志贺毒素大肠杆菌菌株中发现的丝氨酸蛋白酶细胞毒素编码 subAB 操纵子。

Subtilase cytotoxin-encoding subAB operon found exclusively among Shiga toxin-producing Escherichia coli strains.

机构信息

Department of Bacteriology, Instituto Adolfo Lutz. Av. Dr Arnaldo, 351/355, 9 andar, CEP 01246-902 São Paulo, SP, Brazil.

出版信息

J Clin Microbiol. 2010 Mar;48(3):988-90. doi: 10.1128/JCM.00010-10. Epub 2010 Jan 20.

DOI:10.1128/JCM.00010-10
PMID:20089761
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2832406/
Abstract

The presence of subAB was investigated for 3,453 Escherichia coli strains of various pathogenic categories. The occurrence of other virulence genes in subAB-positive strains was investigated. The subAB operon was detected among some Shiga toxin-producing E. coli (STEC) serotypes devoid of eae and carrying ehxA. Most subAB-positive strains also harbored stx2, iha, saa, and lpfA(O113).

摘要

研究了来自各种致病类别的 3453 株大肠杆菌菌株中 subAB 的存在情况。研究了 subAB 阳性菌株中其他毒力基因的发生情况。在一些不携带 eae 但携带 ehxA 的产志贺毒素大肠杆菌 (STEC) 血清型中检测到 subAB 操纵子。大多数 subAB 阳性菌株还携带 stx2、iha、saa 和 lpfA(O113)。

相似文献

1
Subtilase cytotoxin-encoding subAB operon found exclusively among Shiga toxin-producing Escherichia coli strains.仅在产志贺毒素大肠杆菌菌株中发现的丝氨酸蛋白酶细胞毒素编码 subAB 操纵子。
J Clin Microbiol. 2010 Mar;48(3):988-90. doi: 10.1128/JCM.00010-10. Epub 2010 Jan 20.
2
Transcription of the Subtilase Cytotoxin Gene in Shiga Toxin-Producing Escherichia coli Is Dependent on and .志贺毒素产生大肠杆菌中枯草溶菌素毒素基因的转录依赖于 和 。
Appl Environ Microbiol. 2019 Oct 1;85(20). doi: 10.1128/AEM.01281-19. Print 2019 Oct 15.
3
Identification of the newly identified subtilase cytotoxin-encoding gene (subAB2-2) among clinical Shiga toxin-producing Escherichia coli isolates.在临床产志贺毒素大肠杆菌分离株中鉴定新发现的枯草杆菌蛋白酶细胞毒素编码基因(subAB2-2)。
Can J Microbiol. 2015 Dec;61(12):990-4. doi: 10.1139/cjm-2015-0519. Epub 2015 Oct 21.
4
Prevalence of subtilase cytotoxin-encoding subAB variants among Shiga toxin-producing Escherichia coli strains isolated from wild ruminants and sheep differs from that of cattle and pigs and is predominated by the new allelic variant subAB2-2.从野生反刍动物和绵羊中分离出的产志贺毒素大肠杆菌菌株中,枯草杆菌蛋白酶细胞毒素编码亚基AB变体的流行情况与牛和猪不同,且以新的等位基因变体subAB2-2为主。
Int J Med Microbiol. 2015 Jan;305(1):124-8. doi: 10.1016/j.ijmm.2014.11.009. Epub 2014 Nov 20.
5
A new pathogenicity island carrying an allelic variant of the Subtilase cytotoxin is common among Shiga toxin producing Escherichia coli of human and ovine origin.一个携带枯草溶菌素细胞毒素等位变异体的新致病性岛普遍存在于人和羊源产志贺毒素大肠杆菌中。
Clin Microbiol Infect. 2013 Mar;19(3):E149-56. doi: 10.1111/1469-0691.12122. Epub 2013 Jan 17.
6
Prevalences of Shiga toxin subtypes and selected other virulence factors among Shiga-toxigenic Escherichia coli strains isolated from fresh produce.从新鲜农产品中分离的产志贺毒素大肠杆菌菌株中志贺毒素亚型和其他选定毒力因子的流行率。
Appl Environ Microbiol. 2013 Nov;79(22):6917-23. doi: 10.1128/AEM.02455-13. Epub 2013 Aug 30.
7
Virulence characteristics of Shiga toxin-producing Escherichia coli from raw meats and clinical samples.来自生肉和临床样本的产志贺毒素大肠杆菌的毒力特征。
Microbiol Immunol. 2015 Mar;59(3):114-22. doi: 10.1111/1348-0421.12235.
8
Subtilase cytotoxin encoding genes are present in human, sheep and deer intimin-negative, Shiga toxin-producing Escherichia coli O128:H2.在产志贺毒素大肠杆菌 O128:H2 中,存在于人类、绵羊和鹿的紧密素阴性菌株中的梭菌细胞毒素编码基因。
Vet Microbiol. 2012 Oct 12;159(3-4):531-5. doi: 10.1016/j.vetmic.2012.04.036. Epub 2012 May 3.
9
The new allelic variant of the subtilase cytotoxin (subAB2) is common among Shiga toxin-producing Escherichia coli strains from large game animals and their meat and meat products.新的枯草溶菌素细胞毒素(subAB2)等位基因变异体在来自大型猎物及其肉类和肉类产品的产志贺毒素大肠杆菌菌株中很常见。
Vet Microbiol. 2013 Oct 25;166(3-4):645-9. doi: 10.1016/j.vetmic.2013.06.031. Epub 2013 Jul 9.
10
Distribution of virulence profiles related to new toxins and putative adhesins in Shiga toxin-producing Escherichia coli isolated from diverse sources in Brazil.从巴西不同来源分离的产志贺毒素大肠杆菌中与新毒素和假定黏附素相关的毒力谱分布
FEMS Microbiol Lett. 2007 Sep;274(2):329-34. doi: 10.1111/j.1574-6968.2007.00856.x. Epub 2007 Jul 25.

引用本文的文献

1
AB Enterotoxin-Mediated Pathogenesis: Perspectives Gleaned from Shiga Toxins.AB 肠毒素介导的发病机制:从志贺毒素中获得的观点。
Toxins (Basel). 2022 Jan 16;14(1):62. doi: 10.3390/toxins14010062.
2
Combined Action of Shiga Toxin Type 2 and Subtilase Cytotoxin in the Pathogenesis of Hemolytic Uremic Syndrome.志贺毒素 2 型与枯草溶菌素细胞毒素在溶血性尿毒综合征发病机制中的共同作用。
Toxins (Basel). 2021 Jul 29;13(8):536. doi: 10.3390/toxins13080536.
3
Virulence Profiling and Molecular Typing of Shiga Toxin-Producing (STEC) from Human Sources in Brazil.巴西人类源产志贺毒素大肠杆菌(STEC)的毒力分析与分子分型
Microorganisms. 2020 Jan 25;8(2):171. doi: 10.3390/microorganisms8020171.
4
Mechanism of inhibition of Shiga-toxigenic SubAB cytotoxicity by steroids and diacylglycerol analogues.类固醇和二酰基甘油类似物抑制志贺毒素性SubAB细胞毒性的机制。
Cell Death Discov. 2018 Feb 14;4:22. doi: 10.1038/s41420-017-0007-4. eCollection 2018 Dec.
5
Detection and Characterization of Enteropathogenic and Shiga Toxin-Producing Strains in spp. from Buenos Aires.布宜诺斯艾利斯地区 种属中肠致病性和产志贺毒素菌株的检测与鉴定
Front Microbiol. 2018 Feb 14;9:199. doi: 10.3389/fmicb.2018.00199. eCollection 2018.
6
Emerging types of Shiga toxin-producing E. coli (STEC) O178 present in cattle, deer, and humans from Argentina and Germany.在来自阿根廷和德国的牛、鹿及人类体内发现的新型产志贺毒素大肠杆菌(STEC)O178 。
Front Cell Infect Microbiol. 2014 Jun 17;4:78. doi: 10.3389/fcimb.2014.00078. eCollection 2014.
7
Effects of Escherichia coli subtilase cytotoxin and Shiga toxin 2 on primary cultures of human renal tubular epithelial cells.大肠杆菌枯草溶菌素细胞毒素和志贺毒素 2 对人肾小管上皮细胞原代培养物的影响。
PLoS One. 2014 Jan 21;9(1):e87022. doi: 10.1371/journal.pone.0087022. eCollection 2014.
8
Occurrence of subtilase cytotoxin and relation with other virulence factors in verocytotoxigenic Escherichia coli isolated from food and cattle in Argentina.从阿根廷食品和牛源中产志贺毒素大肠埃希氏菌中检测到的枯草溶菌素细胞毒素及其与其他毒力因子的关系。
Braz J Microbiol. 2011 Apr;42(2):711-5. doi: 10.1590/S1517-838220110002000037. Epub 2011 Jun 1.
9
Prevalences of Shiga toxin subtypes and selected other virulence factors among Shiga-toxigenic Escherichia coli strains isolated from fresh produce.从新鲜农产品中分离的产志贺毒素大肠杆菌菌株中志贺毒素亚型和其他选定毒力因子的流行率。
Appl Environ Microbiol. 2013 Nov;79(22):6917-23. doi: 10.1128/AEM.02455-13. Epub 2013 Aug 30.
10
Shiga toxin-producing Escherichia coli in yaks (Bos grunniens) from the Qinghai-Tibetan Plateau, China.中国青藏高原牦牛(Bos grunniens)中的产志贺毒素大肠杆菌。
PLoS One. 2013 Jun 11;8(6):e65537. doi: 10.1371/journal.pone.0065537. Print 2013.

本文引用的文献

1
Prevalence of the operon encoding subtilase cytotoxin in non-O157 Shiga toxin-producing Escherichia coli isolated from humans in the United States.在美国从人类分离出的非O157产志贺毒素大肠杆菌中编码枯草杆菌蛋白酶细胞毒素操纵子的流行情况。
J Clin Microbiol. 2009 Sep;47(9):3058-9. doi: 10.1128/JCM.00706-09. Epub 2009 Jul 1.
2
Prevalence and characterization of verotoxin-producing Escherichia coli (VTEC) in cattle from an Ontario abattoir.安大略省一家屠宰场牛群中产志贺毒素大肠杆菌(VTEC)的流行情况及特征
Can J Vet Res. 2008 Jul;72(4):297-302.
3
Diversity of virulence profiles of Shiga toxin-producing Escherichia coli serotypes in food-producing animals in Brazil.巴西产食用动物中产志贺毒素大肠杆菌血清型毒力谱的多样性。
Int J Food Microbiol. 2008 Sep 30;127(1-2):139-46. doi: 10.1016/j.ijfoodmicro.2008.06.023. Epub 2008 Jul 1.
4
Virulence properties and antimicrobial susceptibility of Shiga toxin-producing Escherichia coli strains isolated from healthy cattle from Paraná State, Brazil.从巴西巴拉那州健康牛群中分离出的产志贺毒素大肠杆菌菌株的毒力特性及抗菌药敏性
Can J Microbiol. 2008 Jul;54(7):588-93. doi: 10.1139/w08-046.
5
Distribution of virulence profiles related to new toxins and putative adhesins in Shiga toxin-producing Escherichia coli isolated from diverse sources in Brazil.从巴西不同来源分离的产志贺毒素大肠杆菌中与新毒素和假定黏附素相关的毒力谱分布
FEMS Microbiol Lett. 2007 Sep;274(2):329-34. doi: 10.1111/j.1574-6968.2007.00856.x. Epub 2007 Jul 25.
6
Water buffaloes (Bubalus bubalis) identified as an important reservoir of Shiga toxin-producing Escherichia coli in Brazil.在巴西,水牛(Bubalus bubalis)被确定为产志贺毒素大肠杆菌的重要宿主。
Appl Environ Microbiol. 2007 Sep;73(18):5945-8. doi: 10.1128/AEM.00929-07. Epub 2007 Jul 20.
7
Phenotypic and genotypic traits of Shiga toxin-producing Escherichia coli strains isolated from beef cattle from Paraná State, southern Brazil.从巴西南部巴拉那州肉牛中分离出的产志贺毒素大肠杆菌菌株的表型和基因型特征。
Lett Appl Microbiol. 2007 Jun;44(6):607-12. doi: 10.1111/j.1472-765X.2007.02123.x.
8
Virulence markers and serotypes of Shiga toxin-producing Escherichia coli, isolated from cattle in Rio Grande do Sul, Brazil.从巴西南里奥格兰德州的牛身上分离出的产志贺毒素大肠杆菌的毒力标记和血清型。
Lett Appl Microbiol. 2007 Apr;44(4):419-25. doi: 10.1111/j.1472-765X.2006.02085.x.
9
The operon encoding SubAB, a novel cytotoxin, is present in shiga toxin-producing Escherichia coli isolates from the United States.编码新型细胞毒素SubAB的操纵子存在于来自美国的产志贺毒素大肠杆菌分离株中。
J Clin Microbiol. 2007 Apr;45(4):1374-5. doi: 10.1128/JCM.00076-07. Epub 2007 Feb 7.
10
Multiplex PCR for direct detection of Shiga toxigenic Escherichia coli strains producing the novel subtilase cytotoxin.用于直接检测产生新型枯草杆菌蛋白酶细胞毒素的志贺毒素大肠杆菌菌株的多重聚合酶链反应
J Clin Microbiol. 2005 Jun;43(6):2944-7. doi: 10.1128/JCM.43.6.2944-2947.2005.